Skip to main content

Shoulder Ring Complaints as a Rare First Symptom of Malignant Pleural Mesothelioma

  • Chapter
  • First Online:

Part of the book series: Advances in Experimental Medicine and Biology ((NR,volume 852))

Abstract

The prevalence of malignant pleural mesothelioma is often encountered in the areas highly exposed to asbestos. The aim of this paper was a retrospective analysis of shoulder pain as a rare, first symptom of pleural mesothelioma, which constitutes an interdisciplinary diagnostic problem concerning both orthopedics and pulmonology. The research was based on a retrospective review of the patients’ medical records. The considered period of time included the years 2006–2012. The study group included a total of 49 patients. Seven patients (14.3 %) presented a complain of shoulder pain, as the first symptom of mesothelioma. The remaining 42 mesothelioma patients, without this symptom, constituted a reference group. The intensity of shoulder pain was, on average, 4/10 on an analog scale. A concomitant limitation of mobility was observed in five out of the seven subjects. In one case, limitation of motion and dysfunction of the shoulder joint were at an advanced stage. Neuralgia of upper limbs was found in two cases. We conclude that shoulder pain may be a manifesting symptom of malignant pleural mesothelioma. The neoplasm appears to have a pleiotropic effect on human body, reflected in different ways of its primary manifestation which may also include the motor system.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Adamietz B, Sauer R, Keilholz L (2008) Radiotherapy for shoulder impingement. Strahlenther Onkol 184(5):245–250

    Article  PubMed  Google Scholar 

  • Aziz T, Jilaihawi A, Prakash D (2002) The management of malignant pleural mesothelioma; single centre experience in 10 years. Eur J Cardiothorac Surg 22(2):298–305

    Article  PubMed  Google Scholar 

  • Caravatti M, Jan-Wehrle S, Uebelhart D (2001) Conservative treatment of shoulder disorders. Ther Umsch 58(8):475–479

    Article  CAS  PubMed  Google Scholar 

  • Carbone M, Ly BH, Dodson RF, Pagano I, Morris PT, Dogan UA, Gazdar AF, Pass HI, Yang H (2012) Malignant mesothelioma: facts, myths, and hypotheses. J Cell Physiol 227(1):44–58

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Delgermaa V, Takahashi K, Park EK, Le GV, Hara T, Sorahan T (2011) Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008. Bull World Health Organ 89(10):716–724, 724A–724C

    Article  PubMed Central  PubMed  Google Scholar 

  • Konieczko K, Pałaszewska-Tkacz A, Czerczak S (2013) Chemical carcinogenic and mutagenic agents in the workplace, Poland, 2008–2010. Med Pr 64(2):181–192

    CAS  PubMed  Google Scholar 

  • Lee S, Matsuzaki H, Kumagai-Takei N, Yoshitome K, Maeda M, Chen Y, Kusaka M, Urakami K, Hayashi H, Fujimoto W, Nishimura Y, Otsuki T (2014) Silica exposure and altered regulation of autoimmunity. Environ Health Prev Med 19(5):322–329

    Article  CAS  PubMed  Google Scholar 

  • Mazel JA, Roolvink EG (1997) Clinical judgment and decision making in medical practice. A patient with shoulder symptoms. Ned Tijdschr Geneeskd 15:2234–2238

    Google Scholar 

  • Mott FE (2012) Mesothelioma: a review. Ochsner J 12(1):70–79

    PubMed Central  PubMed  Google Scholar 

  • NCCN (2013) NCCN clinical practice guidelines in oncology. Malignant pleural mesothelioma. Version I. Available from: http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed on 31 May 2013

  • Neumann V, Löseke S, Nowak D (2013) Malignant pleural mesothelioma. Incidence, etiology, diagnosis. Incidence, etiology, diagnosis, treatment and occupational health. Dtsch Ärztebl Int 110(18):319–326

    PubMed Central  PubMed  Google Scholar 

  • Opitz I (2014) Management of malignant pleural mesothelioma-The European experience. J Thorac Dis 6(suppl 2):38–52

    Google Scholar 

  • Park EK, Takahashi K, Hoshuyama T, Cheng TJ, Delgermaa V, Le GV, Sorahan T (2011) Global magnitude of reported and unreported mesothelioma. Environ Health Perspect 119(4):514–518

    Article  PubMed Central  PubMed  Google Scholar 

  • Pfau JC, Serve KM, Noonan CW (2014) Autoimmunity and asbestos exposure. Autoimmun Dis 2014:782045

    Google Scholar 

  • Ramponi DR (2011) Shoulder pain. Adv Emerg Nurs J 33(2):114–126

    Article  PubMed  Google Scholar 

  • Robinson BM (2012) Malignant pleural mesothelioma: an epidemiological perspective. Ann Cardiothorac Surg 1(4):491–496

    PubMed Central  PubMed  Google Scholar 

  • Skammeritz E, Omland LH, Johansen JP, Omland O (2011) Asbestos exposure and survival in malignant mesothelioma: a description of 122 consecutive cases at an occupational clinic. Int J Occup Environ Med 2(4):224–236

    CAS  PubMed  Google Scholar 

  • Szeszenia-Dąbrowska N, Swiątkowska B, Szubert Z, Wilczyńska U (2011) Asbestos in Poland: occupational health problems. Intern J Occup Med Environ Health 24(2):142–152

    Google Scholar 

  • Verpeut A, Vansteenkiste J, Deschepper K, Demedts M (1999) Preoperative work-up of a solitary diaphragmatic mass in a patient with right shoulder pain: a case for diagnosis. Monaldi Arch Chest Dis 54(3):234–236

    CAS  PubMed  Google Scholar 

  • Weder W, Opitz I (2012) Multimodality therapy for malignant pleural mesothelioma. Ann Cardiothorac Surg 1(4):502–507

    PubMed Central  PubMed  Google Scholar 

Download references

Conflicts of Interest

The authors declare no conflicts of interest in relation to this article.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to J. Lorkowski .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Lorkowski, J., Grzegorowska, O., Kotela, A., Weryński, W., Kotela, I. (2015). Shoulder Ring Complaints as a Rare First Symptom of Malignant Pleural Mesothelioma. In: Pokorski, M. (eds) Respiratory Carcinogenesis. Advances in Experimental Medicine and Biology(), vol 852. Springer, Cham. https://doi.org/10.1007/5584_2015_113

Download citation

Publish with us

Policies and ethics