Bioactive Surfaces

Volume 240 of the series Advances in Polymer Science pp 1-33


Smart Polymer Surfaces: Concepts and Applications in Biosciences

  • Erik WischerhoffAffiliated withFraunhofer Institute for Applied Polymer Research
  • , Nezha BadiAffiliated withFraunhofer Institute for Applied Polymer Research
  • , André LaschewskyAffiliated withFraunhofer Institute for Applied Polymer ResearchDepartment of Chemistry, University of Potsdam
  • , Jean-François LutzAffiliated withFraunhofer Institute for Applied Polymer Research Email author 

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Stimuli-responsive macromolecules (i.e., pH-, thermo-, photo-, chemo-, and bioresponsive polymers) have gained exponential importance in materials science, nanotechnology, and biotechnology during the last two decades. This chapter describes the usefulness of this class of polymer for preparing smart surfaces (e.g., modified planar surfaces, particles surfaces, and surfaces of three-dimensional scaffolds). Some efficient pathways for connecting these macromolecules to inorganic, polymer, or biological substrates are described. In addition, some emerging bioapplications of smart polymer surfaces (e.g., antifouling surfaces, cell engineering, protein chromatography, tissue engineering, biochips, and bioassays) are critically discussed.


Antifouling surfaces Bioactive surfaces Biocompatible polymers Bioseparation Cell engineering Polymer-modified surfaces Stimuli-responsive polymers