Chapter

Mesenchymal Stem Cells - Basics and Clinical Application II

Volume 130 of the series Advances in Biochemical Engineering/Biotechnology pp 267-286

Date:

Sources of Mesenchymal Stem Cells: Current and Future Clinical Use

  • Michela PozzobonAffiliated withDepartment of Woman and Child Health, University of PadovaCittà della Speranza Foundation
  • , Martina PiccoliAffiliated withDepartment of Woman and Child Health, University of PadovaCittà della Speranza Foundation
  • , Paolo De CoppiAffiliated withDepartment of Pediatrics and Pediatric Surgery, University of PadovaUCL Institute of Child Health, Surgery Unit, Great Ormond Street Hospital, University College Email author 

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Abstract

Despite the lack of international criteria defining the biological properties and surface markers that must possess mesenchymal stem cells (MSC), it become of paramount importance to know the different sources and the clinical applications of these promising stem cells. In this chapter we overview the most important sources of MSC from the inner cell mass of the blastocyst to the adult source and landing to the induced pluripotent stem cells (iPS). Following the criteria defining MSC properties so far observed, we drew the attention on the role of MSC as tool for regenerative medicine and therapeutic purposes.

Graphical Abstract

https://static-content.springer.com/image/chp%3A10.1007%2F10_2012_161/MediaObjects/300442_1_En_161_Figa_HTML.gif

Keywords

Adult MSC Amniotic fluid Adipose tissue Cord blood iPS Therapeutic applications of MSC