Abstract
The halophilic Archaea (order Halobacteriales) form a diverse group of microorganisms adapted to life at high salt concentrations. The cells contain molar concentrations of K+ and Cl− to provide osmotic balance. Enzymes and other proteins require the presence of high salt concentrations for activity and structural stability. Most proteins contain a large excess of acidic amino acids and low amounts of hydrophobic amino acids. The structure resolution of a number of such enzymes by X-ray crystallography and the use of site-directed mutagenesis in recent years has greatly increased our understanding of the adaptation of the Halo-bacteriales to life at high salt concentrations.
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Oren, A. (2002). Adaptation of Halophilic Archaea to Life at High Salt Concentrations. In: Läuchli, A., Lüttge, U. (eds) Salinity: Environment - Plants - Molecules. Springer, Dordrecht. https://doi.org/10.1007/0-306-48155-3_4
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DOI: https://doi.org/10.1007/0-306-48155-3_4
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