Examination of Regulatory Cross-talk Between the Decay Accelerating Factor-binding Fimbrial/Afimbrial Adhesins and Type I Fimbriae

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  1. The revised sequence of DaaA means that the protein is 98% identical to the afimbrial adhesin regulator AFAA-III.

  2. While PapB repressed FimB OFF to ON switching in strain AAEC370A,this was not the case for DaaA.

  3. PapB,but not DaaA,reduced the level of expression of type 1 fimbriae,in static LB media.

  4. Attention is now focused on the amino terminus of the PapB protein as the possible domain involved in cross talk with type 1 fimbriae.