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Valutazione RM del fascio neurovascolare e grado di deficit funzionale nel paziente prostatectomizzato

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Riassunto

L’intervento di prostatectomia radicale con tecnica nerve-sparing assicura un buon controllo a lungo termine del carcinoma prostatico in pazienti con malattia locoregionale [1]. La disfunzione erettile rappresenta una delle complicanze più frequenti dopo l’intervento chirurgico e il recupero della funzionalità è direttamente correlabile con il grado di integrità anatomica del fascio neurovascolare periprostatico (FNVP) [1]. Recenti studi sono stati incentrati sulla valutazione preoperatoria di questa struttura per un corretto planning terapeutico e alcuni autori affermano che un completo studio morfologico del FNVP prima dell’intervento — considerata la notevole variabilità individuale del suo percorso anatomico — riduce significativamente la percentuale di lesioni iatrogene da resezione accidentale [2, 3]. Non da ultimo, le teorie più recenti hanno introdotto il concetto di “neurapraxia”, che letteralmente comprende il fallimento della conduzione dello stimolo nervoso, senza evidenti cambiamenti morfologici, dovuto a lesioni da compressione, stiramento o ischemia, che sarebbero responsabili del ritardo nel recupero della funzionalità erettile postoperatoria [4, 5].

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Bibliografia

  1. Rabbani F, Stapleton AM, Kattan MW et al (2000) Factors predicting recovery of erections after radical prostatectomy. J Urol 164:1929–1934

    Article  CAS  PubMed  Google Scholar 

  2. Lunacek A, Schwentner C, Fritsch H et al (2005) Anatomical radical retropubic prostatectomy: “curtain dissection” of the neurovascular bundle. BJU Int 95:1226–1231

    Article  PubMed  Google Scholar 

  3. Costello AJ, Brooks M, Cole OJ (2004) Anatomical studies of the neurovascular bundle and cavernosal nerves. BJU Int 94:1071–1076

    Article  PubMed  Google Scholar 

  4. Newman Dorland WA (1988) Dorland’s Illustrated Medical Dictionary (27th ed). WB Saunders Company, Philadelphia, p 1126

    Google Scholar 

  5. McCullough AR (2001) Prevention and management of erectile dysfunction following radical prostatectomy. Urol Clin North Am 28:613–627

    Article  CAS  PubMed  Google Scholar 

  6. Montorsi F, Guazzoni G, Strambi LF et al (1997) Recovery of spontaneous erectile function after nerve-sparing radical retropubic prostatectomy with and without early intracavernous injections of alprostadil: results of a prospective, randomized trial. J Urol 158(4):1408–1410

    Article  CAS  PubMed  Google Scholar 

  7. Sim HG, Kliot M, Lange PH et al (2006) Two-year outcome of unilateral sural nerve interposition graft after radical prostatectomy. Urology 68(6):1290–1294

    Article  PubMed  Google Scholar 

  8. Bloch BN, Furman-Haran E, Helbich TH et al (2007) Prostate cancer: accurate determination of extracapsular extension with high-spatial-resolution dynamic contrast-enhanced and T2-weighted MR imaging-initial results. Radiology 245(1):176–185

    Article  PubMed  Google Scholar 

  9. Ogura K, Maekawa S, Okubo K et al (2001) Dynamic endorectal magnetic resonance imaging for local staging and detection of neurovascular bundle involvement of prostate cancer: correlation with histopathologic results. Urology 57: 721–726

    Article  CAS  PubMed  Google Scholar 

  10. Hricak H, Wang L, Wei DC et al (2004) The role of preoperative endorectal magnetic resonance imaging in the decision regarding whether to preserve or resect neurovascular bundles during radical retropubic prostatectomy. Cancer 100(12):2655–2663

    Article  PubMed  Google Scholar 

  11. Lee SE, Hong SK, Han JH et al (2007) Significance of neurovascular bundle formation observed on preoperative magnetic resonance imaging regarding postoperative erectile function after nerve-sparing radical retropubic prostatectomy. Urology 69(3):510–514

    Article  PubMed  Google Scholar 

  12. Panebianco V, Sciarra A, Osimani M et al (2009) 2D and 3D T2-weighted MR sequences for the assessment of neurovascular bundle changes after nerve-sparing radical retropubic prostatectomy with erectile function correlation. Eur Radiol 19(1):220–229

    Article  PubMed  Google Scholar 

  13. Viallon M, Vargas MI, Jlassi H et al (2008) High-resolution and functional magnetic resonance imaging of the brachial plexus using an isotropic 3D T2 STIR (Short Term Inversion Recovery) SPACE sequence and diffusion tensor imaging. Eur Radiol 18(5):1018–1023

    Article  CAS  PubMed  Google Scholar 

  14. Mulhall JP (2008) Penile rehabilitation following radical prostatectomy. Curr Opin Urol 18(6):613–620

    Article  PubMed  Google Scholar 

  15. Burnett AL, Lue TF (2006) Neuromodulatory therapy to improve erectile function recovery outcomes after pelvic surgery. J Urol 176(3):882–887

    Article  PubMed  Google Scholar 

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Panebianco, V., Osimani, M., Gentile, V. (2010). Valutazione RM del fascio neurovascolare e grado di deficit funzionale nel paziente prostatectomizzato. In: Passariello, R., Panebianco, V., Di Silverio, F., Sciarra, A. (eds) Imaging RM della prostata. Springer, Milano. https://doi.org/10.1007/978-88-470-1516-6_22

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  • DOI: https://doi.org/10.1007/978-88-470-1516-6_22

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-1515-9

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