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Raman Spectroscopy: A Tool for Tissue Engineering

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Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

Abstract

Raman spectroscopy can offer a non-invasive, information-rich biochemical “snapshot” of living human cells, tissues or material-cell tissue constructs rapidly(seconds–minutes), without the need of labels or contrast enhancers. This chapter details the exciting potential and challenges associated with the use of Raman spectroscopy in tissue engineering (TE). The use of Raman spectroscopy in three interlinked areas of TE will be considered: (1) the characterisation of the various scaffolds and “smart” materials, (2) the biochemical analysis of cellular behaviour important in TE (e.g. differentiation) and (3) the use of Raman spectroscopy for the analysis of tissue/extracellular matrix (ECM) formation in vitro or possibly in vivo.

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Authors and Affiliations

  1. Department of Materials and Institute of Biomedical Engineering, Imperial College, London, SW7 2AZ, UK

    Gavin Jell, Robin Swain & Molly M. Stevens

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  1. Gavin Jell
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  2. Robin Swain
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  3. Molly M. Stevens
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Correspondence to Gavin Jell .

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Editors and Affiliations

  1. Science & Technology Facilities Council, Central Laser Facility, Didcot, Oxon., OX11 0QX, United Kingdom

    Pavel Matousek

  2. Dept. Chemistry, University of Michigan, Ann Arbor, 48109-1055, U.S.A.

    Michael D. Morris

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Jell, G., Swain, R., M. Stevens, M. (2010). Raman Spectroscopy: A Tool for Tissue Engineering. In: Matousek, P., Morris, M. (eds) Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02649-2_18

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  • DOI: https://doi.org/10.1007/978-3-642-02649-2_18

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