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Effect of PTH on Osteocyte Ultrastructure

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 103))

Abstract

Parathyroid hormone (PTH) has been shown to cause an increase in the fraction of activated osteocytes, to induce periosteocytic osteolysis, to produce histochemical changes in osteocytes and to affect osteocyte ultrastructure (1,2,3). Analogous findings have been observed in osteocytes of patients suffering from primary or secondary hyperparathyroidism (4,5,6,7).

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References

  1. Porte, J., Meunier, P., Bernard, J., Roche, M.: L’ostéolyse periostéocytaire dans l’hyperparathyréoidisme experimental induit par l’EDTA. Influence de la calcitonine Path.Biol. 20, 775–779, 1972

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  2. Jande, S.S.: Effects of Parathormone on Osteocytes and their Surrounding Matrix. Z. Zellforsch. 130, 463, 1972

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  3. Bélanger, L.F.: Osteolysis: an Outlook on its Mechanism and Causation. In: Gaillard, P.J., Talmage R.V., Budy, A.M., eds.: The Parathyroid Glands: Ultr,astructure, Secretion and Function, p. 137, Chicago Univ. Press, 1965

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  4. Recklinghausen, F.: Untersuchungen Ober Rachitis und Osteomalacie, Jena: G. Fischer 1910

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  5. Krempien, B., E. Ritz, G. Geiger: Behaviour of Osteocytes in Various Ages in Chronic Uremia. Morphological Studies in Human Cortical Bone, in: Proc. Ist Workshop on Bone Morphometry, Z.F.G. Jaworsky, S. Klosevyck eds., Univ. of Ottawa Press, 1976

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  6. Bonucci, E.: Ultrastructural Aspects of Bone Mineralisation in Renal Osteodystrophy, in: Phosphate Metabolism eds.: Shaul Massry, E. Ritz, Advances in Experimental Medicine and Biology, vol. 81, 477, Plenum Press, New York-London, 1977

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  7. Bonucci, E., G. Gherardi: Osteocyte Ultrastructure in Renal Osteodystrophy, Virchows Arch. A 373, 213–231, 1977

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  8. Rasmussen, H., P. Bordier: The Physiological and Cellular Basis of Metabolic Bone Disease, Williams and Wilkins Co., Baltimore, 1974

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© 1978 Plenum Press, New York

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Krempien, B., Friedrich, E., Ritz, E. (1978). Effect of PTH on Osteocyte Ultrastructure. In: Massry, S.G., Ritz, E., Rapado, A. (eds) Homeostasis of Phosphate and Other Minerals. Advances in Experimental Medicine and Biology, vol 103. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7758-0_45

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  • DOI: https://doi.org/10.1007/978-1-4684-7758-0_45

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7760-3

  • Online ISBN: 978-1-4684-7758-0

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