Abstract
A goal of molecular population genetics is to provide an historical understanding of evolutionary processes occurring within and between closely related populations. While molecular techniques can, in principle, be applied to any species, the use of a model system such as Drosophila melanogasterhas proved to be enormously fruitful. One recent finding demonstrates the utility of using a well characterized genetic system: Levels of (presumably) neutral DNA variation are positively correlated with recombination rates in D. melanogaster.1 In this chapter we discuss recent results from our lab which extend this early result, discuss competing models to explain the pattern, and discuss empirical approaches to distinguish among these models.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
D. J. Begun, and C. F. Aquadro. (1992).Nature356, 519–520.
M. Kimura. (1983).The Neutral Theory of Molecular EvolutionCambridge University Press.
J. Maynard Smith, and J. Haigh. (1974).Genet. Res.23, 23–35.
N. L. Kaplan, R. R. Hudson, and C. H. Langley. (1989).Genetics123, 887–899.
W. Stephan, T. H. E. Wiehe, and M. W. Lenz. (1992).Theor. Pop. Biol.41, 237–254.
C. W. Birky Jr., and J. B. Walsh. (1988).Proc. Natl. Acad. Sci U.S.A.85, 6414–6418.
R. R. Hudson. (1990).Oxf. Surv. Evol. Biol.7, 1–44.
M. Aguadè, N. Miyashita, and C. H. Langley. (1989).Genetics122, 607–615.
W. Stephan, and C. H. Langley. (1989).Genetics121, 89–99.
W. Stephan, and S. J. Mitchell. (1992).Genetics312, 1039–1045.
D. J. Begun, and C. F. Aquadro. (1991).Genetics129, 1147–1158.
A. J. Berry, J. W. Ajioka, and M. Kreitman. (1991).Genetics129, 1111–1117.
J. M. MartÃn-Campos, J. M. Comerón, N. Miyashita, and M. Aguadè. (1992).
C. H. Langley, J. MacDonald, N. Miyashita, and M. AguadAAA, M. (1993).Proc. Natl. Acad. Sci. USA90, 1800–1803.
E. C. Kindahl, and C. F. Aquadro. (unpublished).
B. Charlesworth, M. T. Morgan, and D. Charlesworth. (1993).Genetics134, 1289–1303.
B. Charlesworth, J. A. Coyne, and N. H. Barton. (1987).Amer. Nat.130, 113–146.
D. J. Begun, and C. F. Aquadro. (1993).Nature356, 548–550.
C. F. Aquadro, and D. J. Begun. (1993). InMolecular Paleo-population Biology(N. Takahata, A. G. Clark, eds) Japan Sci. Soc. Press/Sinauer.
T.H.E. Wiehe, and W. Stephan. (1993).Molec. Biol. Evol.10, 842–854.
C. F. Aquadro. (1993).Trends Genet.8, 355–362.
J.H. Gillespie. (1991).The Causes of Molecular EvolutionOxford University Press.
J.H.McDonald, and M. Kreitman. (1991).Nature351, 652–654.
W. F. Eanes, M. Kirchner, and J. Yoon. (1993).Proc. Natl. Acad. Sci. USA90, 7475–7479.
R. M. Kliman, and J. Hey. (1993).Genetics133, 375–387.
J. Hey, and R. M. Kliman (1993).Molec. Biol. Evol.10, 804–822.
F. J. Ayala, and D. L. Hartl. (1993).Molec. Biol. Evol.10, 1030–1040.
T. Maruyama, and P. A. Fuerst. (1984).Genetics108, 745–763.
C. H. Langley. (1990). InPopulation Biology of Genes and Molecules(N. Takahata, J. F. Crow) Baifukan Co. Ltd., Tokyo.
F. Tajima. (1993). inMolecular Paleo-population Biology(N. Takahata, A. G. Clark, eds) Japan Sci. Soc. Press/Sinauer.
.M. Aguadè, M. Meyers, A. D. Long, C. H. Langley. (in press).Proc. Natl. Acad. Sci. USA.
J. R. David, and P. Capy. (1988).Trends Genet.4, 106–111.
R. S. Singh, D. A. Hickey, and J. R. David. (1982).Genetics101, 235–256.
M. Choudhary, and R. S. Singh. (1987).Genetics117, 697–710.
R. S. Singh, and L. R. Rhomberg. (1987).Genetics117, 255–271.
J. Sved. (1977). InProceedings of the International on Quantitative GeneticsIowa State University Press.
R. M. Kliman, and J. Hey. (1993).Molec. Biol. Evol10, 1239–1258.
C. F. Aquadro, K. M. Lado, and W. A. Noon. (1988).Genetics119, 875–888.
E. C. Kindahl, and C. F. Aquadro. (unpublished).
R. R. Hudson. (1982).Genetics100, 711–719.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Aquadro, C.F., Begun, D.J., Kindahl, E.C. (1994). Selection, Recombination, and DNA Polymorphism in Drosophila . In: Golding, B. (eds) Non-Neutral Evolution. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2383-3_4
Download citation
DOI: https://doi.org/10.1007/978-1-4615-2383-3_4
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-412-05391-7
Online ISBN: 978-1-4615-2383-3
eBook Packages: Springer Book Archive