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Evolution of Cardio-Metabolic Risk from Birth to Middle Age

The Bogalusa Heart Study

  • Book
  • © 2011
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Overview

Editors:
  1. Gerald S. Berenson

    1. , Department of Epidemiology, Tulane University, New Orleans, USA

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  • Early Natural History of Adults Heart Diseases
  • Adults Heart Diseases beginning in Youth
  • Silent” Coronary Artery Disease, Hypertension, Diabetes
  • Cardio-metabolic Syndrome, Obesity, Cardiovascular Disease
  • Healthy and Unhealthy Living
  • Birth Weight and Heart Disease
  • Preventive Cardiology
  • Includes supplementary material: sn.pub/extras

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Table of contents (14 chapters)

  1. Front Matter

    Pages 1-1
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  2. Exploring Chromosomal Leukocyte Telomere Length Dynamics in the Bogalusa Heart Study

    • Abraham Aviv, Wei Chen
    Pages 1-8
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  3. Fetal Origins of Variables Related to Cardio-Metabolic Risk

    • Sathanur R. Srinivasan
    Pages 9-20
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  4. Trajectories of Variables Related to Cardio-Metabolic Risk from Childhood to Young Adulthood

    • Sathanur R. Srinivasan, JiHua Xu
    Pages 21-33
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  5. Evolution of Metabolic Syndrome from Childhood

    • Wei Chen
    Pages 35-52
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  6. Black–White Divergence Influencing Impaired Fasting Glucose and Type 2 Diabetes Mellitus

    • Quoc Manh Nguyen, Sathanur R. Srinivasan, Gerald S. Berenson
    Pages 53-63
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  7. Birth Weight, Stimulus Response and Hemodynamic Variability Implicate Racial (Black–White) Contrasts of Autonomic Control of Heart Rate and Blood Pressure and Related Cardiovascular Disease

    • Gerald S. Berenson, Pronabesh DasMahapatra, Camilo Fernandez Alonso, Wei Chen, Jihua Xu, Thomas Giles et al.
    Pages 65-76
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  8. Obesity—Findings from the Bogalusa Heart Study

    • David S. Freedman, Heidi M. Blanck
    Pages 77-92
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  9. Morbid Obesity and Premature Death in the Young

    • Pronabesh DasMahapatra, Camilo Fernandez Alonso
    Pages 93-97
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  10. Target Organ Damage Related to Cardiovascular Risk Factors in Youth

    • Elaine M. Urbina
    Pages 99-131
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  11. The Cardiovascular Risk in Young Finns Study and the Special Turku Coronary Risk Factor Intervention Project (STRIP)

    • Markus Juonala, Costan G. Magnussen, Olli Simell, Harri Niinikoski, Olli T. Raitakari, Jorma S. A. Viikari
    Pages 133-141
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  12. Prevention of Heart Disease in Childhood—Encouragement of Primordial Prevention

    • Gerald S. Berenson, Arthur Pickoff
    Pages 143-153
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  13. Dietary Intake of Children over Two Decades in a Community and an Approach for Modification

    • Theresa A. Nicklas, Carol E. O’Neil
    Pages 155-183
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  14. Cardiovascular Health Promotion—Physical Fitness in the School Setting

    • Marietta Orlowski, James Ebert, Arthur Pickoff
    Pages 185-197
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  15. Primordial Prevention Through School Health Promotion

    • Gerald S. Berenson, Sandra Owen
    Pages 199-208
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  16. Back Matter

    Pages 205-205
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Keywords

About this book

That precursors of adult coronary artery disease, hypertension, and type II diabetes begin in childhood have been clearly established by the Bogalusa Heart Study. This unique research program has been able to follow a biracial (black/white) population over 35 years from childhood through mid-adulthood to provide perspectives on the natural history of adult heart diseases. Not only do these observations describe trajectories of cardio-metabolic risk variables leading to these diseases but provide a rationale for the need to begin prevention beginning in childhood. The trajectories of the burden of cardio-metabolic risk variables in the context of their fetal origin and chromosome telomere dynamics provide some insight into the metabolic imprinting in utero and aging process. The observed racial contrasts on cardio-metabolic risk variables implicate various biologic pathways interacting with environment contributing to the high morbidity and mortality from related diseases in our population. To address the seriousness of the onset of cardiovascular disease in youth, approaches to primordial prevention are described focussing on childhood health education as an important aspect of Preventive Cardiology.

Editors and Affiliations

  • , Department of Epidemiology, Tulane University, New Orleans, USA

    Gerald S. Berenson

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