GISTs - Gastrointestinal Stromal Tumors

1. Front Matter

   Pages I-XII

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2. Clinical Pathology

   1. Front Matter

      Pages 1-1

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   2. Anatomic and Clinical Pathology

      • Annarosaria De Chiara, Angelo Paolo Dei Tos

      Pages 3-12

3. Imaging

   1. Front Matter

      Pages 13-13

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   2. Introduction

      • Elisabetta de Lutio di Castelguidone

      Pages 15-16

   3. Conventional Radiography

      • Francesco La Seta, Teresa Maria Borino, Lorenzo Tesè, Luigi Carlo Cirillo, Filippo Barbiera

      Pages 17-26

   4. Endoscopy and Endoscopic Ultrasound in the Diagnosis and Staging of GISTs

      • Pietro Marone, Giovanni Battista Rossi, Mario de Bellis, Alfonso Tempesta

      Pages 27-37

   5. Ultrasound, Color-Doppler Ultrasound and Contrast-enhanced Ultrasound of Primary GISTs and Liver Metastases

      • Orlando Catalano, Vincenza Granata

      Pages 39-46

   6. Computed Tomography

      • Elisabetta de Lutio di Castelguidone, Sergio Venanzio Setola, Antonella Messina, Carlo Morosi, Maria Cristina Bellucci, Secondo Lastoria et al.

      Pages 47-70

   7. Magnetic Resonance

      • Antonella Messina, Gianpiero Cardone, Elisabetta de Lutio di Castelguidone, Carlo Morosi, Antonella Petrillo, Daniele Vergnaghi

      Pages 71-86

   8. Contrast-enhanced PET/CT in the Follow-up of GISTs

      • Ennio Biscaldi, Arnoldo Piccardo, Gian Andrea Rollandi

      Pages 87-98

4. Treatment

   1. Front Matter

      Pages 99-99

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   2. Medical Treatment

      • Elena Fumagalli, Gaetano Apice, Paolo Giovanni Casali

      Pages 101-106

   3. Surgical Treatment

      • Alessandro Gronchi, Marco Fiore, Raffaele Palaia

      Pages 107-112

5. Management

   1. Front Matter

      Pages 113-113

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   2. GIST Unit Network

      • Aldo Torreggiani, Stanislao Forte, Sergio Venanzio Setola

      Pages 115-121

6. Back Matter

   Pages 123-124

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This book aims to provide a complete overview of the diagnosis and treatment of gastrointestinal stromal tumors (GISTs). It has been conceived to be both a detailed guide for clinical practice and an updated reference for all those involved in the evaluation of GISTs imaging. The publication provides comprehensive descriptions of the full range of common imaging and non imaging techniques used in the diagnosis and followup of GISTs. Techniques reviewed include: Conventional radiography· Endoscopy and endoscopic ultrasound· Conventional, color-Doppler and contrast-enhanced ultrasound· Computed tomography· Magnetic resonance imaging, and· Contrast-enhanced PET/CT imaging. Both medical and surgical treatment strategies are also fully reviewed. Finally, the book concludes with a chapter that aims to stimulate widespread interest in the formation of new GISTs Units. Written by experts in the field, the book is enriched throughout by numerous black-and-white and color images, making it an invaluable source of information as well as an indispensable guide to interpreting images for radiologists, gastroenterologists, pathologists, oncologists and surgeons.

• Gastrointestinal tract
• MDCT/MR PET/CT/US/CEUS
• Molecular target therapy
• Stromal tumor

From the reviews:

“This is an excellent, concise, comprehensive, well-written book on gastrointestinal stromal tumors (GISTs), which can occur anywhere in the gastrointestinal tract. … The intended audience is oncologists, radiologists, and pathologists. However, trainees in these specialties, physician assistants, nursing personnel, and information technology personnel can also benefit. … highly recommended to individuals who manage patients with GISTs, especially individuals who are in tertiary cancer centers that have a multidisciplinary approach to the treatment of GISTs and tend to manage a large number of these patients.” (Aurelio Matamoros, Jr., The Journal of Nuclear Medicine, Vol. 52 (10), October, 2011)

“A thoughtfully compiled book, containing 11 chapters which address the epidemiology, pathology and molecular biology, imaging/diagnosis, treatment, and follow-up of this unique neoplasm, which can often surprise and fascinate physicians with its wide range of clinical presentations and behaviors. … Overall, the editors have created a text which is useful for any diagnostic radiologist or other clinician … . this is a helpful and well-written text with many beautiful illustrative images, addressing molecular biology, evaluation, and treatment of GI stromal tumors.” (Elena Korngold, Journal of Gastrointestinal Cancer, Vol. 42 (3), May, 2011)

• Radiology Unit, National Cancer Institute G. Pascale, Naples, Italy

  Elisabetta Lutio di Castelguidone

• Department of Radiology and Radiotherapy, National Cancer Institute, Milan, Italy

  Antonella Messina

Elisabetta de Lutio graduated in medicine and specialized in diagnostic imaging at the University of Naples. In her over twenty years of experience, first at A. Cardarelli Hospital (Naples) and now at the G. Pascale Tumor Foundation (Naples), she has been involved in various sectors of diagnostic imaging, including conventional radiology, interventional US, color Doppler, CEUS and MDCT, and become expert in double contrast techniques applied to the musculoskeletal system and the gastrointestinal tract. Her strong interdisciplinary approach has seen her involved in numerous interdepartmental working groups and study protocols, collaborating with colleagues from hematology, surgery, medicine and intensive care in the study of a broad range of oncologic disease, including colorectal cancer, HCC, GIST and breast cancer, as well as studying novel techniques of contrast enhancement. She has also taught in specialization courses in oncology and diagnostic imaging techniques of the gastrointestinal tract.

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