New Principles in Developmental Processes

1. Front Matter

   Pages i-ix

   PDF

2. Making Cells Unequal in a Tissue to Form Embryos and Organs

   1. Front Matter

      Pages 1-1

      PDF

   2. Taxon-Specific Maternal Factors for Germline Specification

      • Gaku Kumano

      Pages 3-11

   3. Establishment of Anterior–Posterior Axis in the Mouse Embryo

      • Katsuyoshi Takaoka

      Pages 13-26

   4. Cell Competition: The Struggle for Existence in Multicellular Communities

      • Kei Kunimasa, Shizue Ohsawa, Tatsushi Igaki

      Pages 27-40

   5. Position-Dependent Hippo Signaling Controls Cell Fates in Preimplantation Mouse Embryos

      • Hiroshi Sasaki

      Pages 41-53

   6. Building Functional Internal Organs from a Naïve Endodermal Sheet

      • Mitsuru Morimoto

      Pages 55-68

3. Choosing a Fate from Multiple Potencies

   1. Front Matter

      Pages 69-69

      PDF

   2. Determination of Stem Cell Fate in Planarian Regeneration

      • Yoshihiko Umesono

      Pages 71-83

   3. Regulation of Axial Stem Cells Deriving Neural and Mesodermal Tissues During Posterior Axial Elongation

      • Tatsuya Takemoto

      Pages 85-96

   4. Tbx1/Ripply3/Retinoic Acid Signal Network That Regulates Pharyngeal Arch Development

      • Tadashi Okubo

      Pages 97-108

4. Cells in a Community of Reorganizing Tissues

   1. Front Matter

      Pages 109-109

      PDF

   2. Interaction of Epithelial Cells and Basement Membrane in the Regulation of EMT Exemplified in Chicken Embryo Gastrulation

      • Yukiko Nakaya

      Pages 111-121

   3. Making the Neural Plate to Fold into a Tube

      • Tamako Nishimura

      Pages 123-136

   4. Contribution of Apoptosis in Cranial Neural Tube Closure Indicated by Mouse Embryo Live Imaging

      • Yoshifumi Yamaguchi, Naomi Shinotsuka, Keiko Nonomura, Masayuki Miura

      Pages 137-147

5. Heterologous Tissue Interactions to Generate a Function

   1. Front Matter

      Pages 149-149

      PDF

   2. Secondary Smad1/5/8-Dependent Signaling Downstream of SHH Determines Digit Identity

      • Takayuki Suzuki

      Pages 151-160

   3. Deciphering Cerebellar Neural Circuitry Involved in Higher Order Functions Using the Zebrafish Model

      • Masahiko Hibi, Takashi Shimizu

      Pages 161-184

   4. Primitive Erythroblast Cell Autonomously Regulates the Timing of Blood Circulation Onset via a Control of Adherence to Endothelium

      • Atsuo Iida

      Pages 185-195

   5. Limb Regeneration: Reconstitution of Complex Organs Using Specific Tissue Interactions

      • Akira Satoh

      Pages 197-210

During the last decade, modern technologies have made a revolutionary change in developmental biology. The molecular and cellular processes in live embryos can now be visualized thanks to technologies using fluorescent proteins. The whole genome information of a wide range of animal species has now become available, confirming the common principles that operate in every species. These and other advances in our understanding of the developmental processes during embryogenesis and tissue regeneration have put forward new principles. Those new principles will also be important in the stem cell biology, branched from developmental biology, in order to generate a particular tissue by manipulating stem cells. This book is planned to introduce these new principles to readers who are working in developmental biology and/or stem cell biology fields, with an emphasis on genetic and cellular processes.    

• cell competition
• embryogenesis
• heterologous tissue
• stem cells
• tissue regeneration

• Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

  Hisato Kondoh

• Graduate School Science, Nagoya University, Nagoya, Japan

  Atsushi Kuroiwa

Hisato Kondoh (PhD. Professor, Graduate School of Frontier Biosciences, Osaka University) Atsushi Kuroiwa (PhD. Professor, Graduate School Science, Nagoya University)

Policies and ethics