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Alzheimer’s Disease - From Basic Research to Clinical Applications

  • Conference proceedings
  • © 1998

Overview

Editors:
  1. H.-J. Gertz

    1. Klinik und Poliklinik für Psychiatrie, Universität Leipzig, Bundesrepublik Deutschland

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  2. Th. Arendt

    1. Paul-Flechsig-Institut für Hirnforschung, Universität Leipzig, Bundesrepublik Deutschland

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Journal of Neural Transmission. Supplementa (NEURAL SUPPL, volume 54)

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Table of contents (31 papers)

  1. Front Matter

    Pages I-VIII
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  2. Alzheimer’s disease: the size of the problem, clinical manifestation and heterogeneity

    • H. Förstl
    Pages 1-8

  3. Progression of Alzheimer’s disease: variability and consistency: ontogenic models, their applicability and relevance

    • B. Reisberg, E. H. Franssen, L. E. M. Souren, S. Auer, S. Kenowsky
    Pages 9-20

  4. Mild cognitive impairment — an early stage of Alzheimer’s disease?

    • O. Almkvist, H. Basun, L. Bäckman, A. Herlitz, L. Lannfelt, B. Small et al.
    Pages 21-29

  5. The prognosis of mild cognitive impairment in the elderly

    • H. Wolf, M. Grunwald, G. M. Ecke, D. Zedlick, S. Bettin, C. Dannenberg et al.
    Pages 31-50

  6. Prevalence of mild cognitive impairment in an elderly community sample

    • J. Schröder, B. Kratz, J. Pantel, E. Minnemann, U. Lehr, H. Sauer
    Pages 51-59

  7. Increase of optical illusion in demented patients

    • B. Weber, L. Frölich, N. Helbing, D. Simminger, J. Fritze, K. Maurer
    Pages 61-67

  8. Age and dementia effect on neuropsychological test performance in very old age — influence of risk factors for dementia

    • F. M. Reischies, D. Felsenberg, R. Geßner, A. Kage, W. Rossius, P. Schlattmann
    Pages 69-76

  9. Neuropathology of Alzheimer’s disease: a critical update

    • K. A. Jellinger, C. Bancher
    Pages 77-95

  10. Evolution of Alzheimer’s disease related cortical lesions

    • H. Braak, E. Braak, J. Bohl, H. Bratzke
    Pages 97-106

  11. What are the relations between Lewy body disease and AD?

    • I. G. McKeith, P. Ince, E. B. Jaros, A. Fairbairn, C. Ballard, J. Grace et al.
    Pages 107-116

  12. The influence of coincidental vascular pathology on symptomatology and course of Alzheimer’s disease

    • F. Pasquier, D. Leys, P. Scheltens
    Pages 117-127

  13. Corpus callosum in Alzheimer’s disease and vascular dementia — a quantitative magnetic resonance study

    • J. Pantel, J. Schröder, M. Essig, R. Minakaran, L. R. Schad, M. Friedlinger et al.
    Pages 129-136

  14. What do we learn from a few familial Alzheimer’s disease cases?

    • C. Haass, R. Baumeister
    Pages 137-145

  15. Aberrancies in signal transduction and cell cycle related events in Alzheimer’s disease

    • T. Arendt, M. Holzer, U. Gärtner, M. K. Brückner
    Pages 147-158

  16. Mechanisms of cell death in Alzheimer disease — immunopathology

    • P. L. McGeer, E. G. McGeer
    Pages 159-166

  17. Pathological immuno-reactions of glial cells in Alzheimer’s disease and possible sites of interference

    • P. Schubert, T. Ogata, H. Miyazaki, C. Marchini, S. Ferroni, K. Rudolphi
    Pages 167-174

  18. Therapeutic strategies based on immunological hypotheses of Alzheimer’s disease

    • H.-J. Möller
    Pages 175-186

  19. Risk factors for Azheimer’s disease during aging. Impacts of glucose/energy metabolism

    • S. Hoyer
    Pages 187-194

  20. Aging, dementia and calcium metabolism

    • S. Kanowski
    Pages 195-200
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Keywords

About this book

As human longevity continues to be extended, so will the impact of age-associated dementia on individual lives and society. Alzheimer’s disease as the most common cause of dementia in the elderly remains a sentinal problem and its underlying pathology is still poorly understood. Available therapeutic strategies require considerable refinement and the development of new therapeutic strategies need input from basic research. Thus continued efforts are necessary both to understand basic mechanisms of the condition and to achieve more powerfull therapies. This volume brings together the reports of basic scientists and clinical investigators. The chapters provide a spectrum of information valuable for clinicians and scientists. This issue bridges the gap between laboratory work in basic science and the development of urgently needed therapeutic strategies. Areas presented are the molecular and cellular biology of the disease, pathogenetic mechanisms and potential therapeutic targets, genetics, risk factors, strategies of prevention and treatment as well as practical aspects of medical and social care for patients with Alzheimer’s disease.

Reviews

"... The review papers are generally excellent, concise, clear, well referenced, and illustrated ... this book would be of value for investigators interested in the neuropathology, immunopathology, and molecular biology of Alzheimer's disease. It would make an excellent addition to libraries as a reference text for many researchers of varied interests." Journal of Neurology, Neurosurgery, and Psychiatry, 68/2000

Editors and Affiliations

  • Klinik und Poliklinik für Psychiatrie, Universität Leipzig, Bundesrepublik Deutschland

    H.-J. Gertz

  • Paul-Flechsig-Institut für Hirnforschung, Universität Leipzig, Bundesrepublik Deutschland

    Th. Arendt

Bibliographic Information

  • Book Title: Alzheimer’s Disease - From Basic Research to Clinical Applications

  • Editors: H.-J. Gertz, Th. Arendt

  • Series Title: Journal of Neural Transmission. Supplementa

  • DOI: https://doi.org/10.1007/978-3-7091-7508-8

  • Publisher: Springer Vienna

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Wien 1998

  • Softcover ISBN: 978-3-211-83112-0Published: 12 November 1998

  • eBook ISBN: 978-3-7091-7508-8Published: 29 June 2013

  • Series ISSN: 0303-6995

  • Edition Number: 1

  • Number of Pages: VIII, 320

  • Number of Illustrations: 37 b/w illustrations, 1 illustrations in colour

  • Additional Information: Special edition of Journal of Neural Transmission, Suppl. 54

  • Topics: Psychiatry, Neurology, Pathology, Human Genetics

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