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Vitamin D Analogs in Cancer Prevention and Therapy

  • Conference proceedings
  • © 2003

Overview

Editors:
  1. Jörg Reichrath

    1. Hautklinik und Poliklinik der Universitätskliniken des Saarlandes, Homburg/Saar

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  2. Wolfgang Tilgen

    1. Hautklinik und Poliklinik der Universitätskliniken des Saarlandes, Homburg/Saar

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  3. Michael Friedrich

    1. Frauenklinik des Universitätsklinikums der Eberhard-Karls-Universität, Tübingen

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Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 164)

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Table of contents (31 papers)

  1. Front Matter

    Pages I-VIII
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  2. Molecular Biology of Vitamin D

    1. Front Matter

      Pages 1-1
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    2. Evolution and Function of Vitamin D

      • Michael F. Holick
      Pages 3-28

    3. Current Understanding of the Function of the Nuclear Vitamin D Receptor in Response to Its Natural and Synthetic Ligands

      • Carsten Carlberg
      Pages 29-42

    4. Approaches to Evaluating the Association of Vitamin D Receptor Gene Polymorphisms with Breast Cancer Risk

      • Michelle Guy, Lorraine C. Lowe, Deborah Bretherton-Watt, Janine L. Mansi, Kay W. Colston
      Pages 43-54

    5. Ligand Structure—Function Relationships in the Vitamin D Endocrine System from the Perspective of Drug Development (Including Cancer Treatment)

      • Anthony W. Norman, M. T. Mizwicki, W. H. Okamura
      Pages 55-82

    6. Antiproliferative Signalling by 1, 25(OH)2D3in Prostate and Breast Cancer Is Suppressed by a Mechanism Involving Histone Deacetylation

      • Claire M. Banwell, Rena Singh, Paul M. Stewart, Milan R. Uskokovic, Moray J. Campbell
      Pages 83-98

    7. Mechanisms Implicated in the Growth Regulatory Effects of Vitamin D Compounds in Breast Cancer Cells

      • Lorraine Lowe, Christina MØrk Hansen, Siddhika Senaratne, Kay W. Colston
      Pages 99-110

    8. Squamous Cell Carcinomas Fail to Respond to the Prodifferentiating Actions of 1,25(OH)2D3: Why?

      • Daniel D. Bikle, Zhongjian Xie, Dean Ng, Chia-Ling Tu, Yuko Oda
      Pages 111-122

    9. A Novel Vitamin D-Regulated Immediate-Early Gene, IEX-1, Alters Cellular Growth and Apoptosis

      • Rajiv Kumar, Mark R. Pittelkow, Jeffrey L. Salisbury, Joseph P. Grande, Hee-Jeong Im, Kathrin A. Feldmann et al.
      Pages 123-134

    10. Extrarenal Sites of Calcitriol Synthesis:The Particular Role of the Skin

      • Bodo Lehmann, Michael Meurer
      Pages 135-145

    11. Cultured Rat Growth Plate Chondrocytes Express Low Levels of 1α-Hydroxylase

      • Lutz Weber, Ulrike Hügel, Jörg Reichrath, Hauke Sieverts, Otto Mehls, Günter Klaus
      Pages 147-149

    12. Gene Amplification and Splice Variants of 25-Hydroxyvitamin D31, α-Hydroxylase (CYP27B1) in Glioblastoma Multiforme— A Possible Role in Tumor Progression?

      • Britta Diesel, Ulrike Fischer, Eckart Meese
      Pages 151-155

    13. Regulation of the 25-Hydroxyvitamin D-1α-Hydroxylase Gene and Its Splice Variant

      • John N. Flanagan, Lilin Wang, Vin Tangpricha, Jörg Reichrath, Tai C. Chen, Michael F. Holick
      Pages 157-167

    14. Combination of Vitamin D Metabolites with Selective Inhibitors of Vitamin D Metabolism

      • Inge Schuster, Helmut Egger, Gerda Herzig, G. Satyanarayana Reddy, Georg Vorisek
      Pages 169-188

    15. Importance Of Cytochrome P450-Mediated Metabolism in the Mechanism of Action of Vitamin D Analogs

      • Sonoko Masuda, Mian Gao, Anqi Zhang, Martin Kaufmann, Glenville Jones
      Pages 189-202

  3. The Vitamin D System in Cancer

    1. Front Matter

      Pages 203-203
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    2. The Role of Vitamin D in Prostate Cancer

      • Aruna V. Krishnan, Donna M. Peehl, David Feldman
      Pages 205-221

    3. Vitamin D Autocrine System and Prostate Cancer

      • Lilin Wang, Lyman W. Whitlatch, John N. Flanagan, Michael F. Holick, Tai C. Chen
      Pages 223-237

    4. Analysis of the Vitamin D System in Cervical Carcinomas, Breast Cancer and Ovarian Cancer

      • Michael Friedrich, Leyla Rafi, Tanja Mitschele, Wolfgang Tilgen, Werner Schmidt, Jörg Reichrath
      Pages 239-246
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Keywords

About this book

 

This volume provides a comprehensive, highly readable overview of the topics discussed at the First International Symposium on "Vitamin D Analogs in Cancer Prevention and Therapy" held in Homburg/Saar, Germany in May 2002. Leading researchers discuss our present knowledge of the vitamin D system in cancer. Topics range from the newest findings in molecular biology, epidemiology, synthesis and metabolism of vitamin D to new concepts for the use of vitamin D analogs in  cancer prophylaxis and treatment. The book provides essential up-to-date information for every researcher or clinician interested in the biology of vitamin D or cancer.

Editors and Affiliations

  • Hautklinik und Poliklinik der Universitätskliniken des Saarlandes, Homburg/Saar

    Jörg Reichrath, Wolfgang Tilgen

  • Frauenklinik des Universitätsklinikums der Eberhard-Karls-Universität, Tübingen

    Michael Friedrich

Bibliographic Information

  • Book Title: Vitamin D Analogs in Cancer Prevention and Therapy

  • Editors: Jörg Reichrath, Wolfgang Tilgen, Michael Friedrich

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-55580-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2003

  • Hardcover ISBN: 978-3-540-00290-1Published: 23 June 2003

  • Softcover ISBN: 978-3-642-62435-3Published: 30 August 2012

  • eBook ISBN: 978-3-642-55580-0Published: 14 March 2013

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: VIII, 432

  • Topics: Oncology, Public Health, Biochemistry, general, Cancer Research

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