Table of contents (12 chapters)

1. Front Matter

   Pages i-x

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2. 

   Book Chapter

   Pages 1-31

   Discovery and Seminal Developments in the CRISPR Field

   • Francisco J. M. Mojica,
   • Roger A. Garrett
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3. 

   Book Chapter

   Pages 33-59

   Occurrence, Diversity of CRISPR-Cas Systems and Genotyping Implications

   • Christine Pourcel,
   • Christine Drevet
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4. 

   Book Chapter

   Pages 61-91

   Evolution and Classification of CRISPR-Cas Systems and Cas Protein Families

   • Kira S. Makarova,
   • Eugene V. Koonin
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5. 

   Book Chapter

   Pages 93-113

   Regulation of CRISPR-Based Immune Responses

   • Zihni Arslan,
   • Edze R. Westra,
   • Rolf Wagner,
   • Ümit Pul
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6. 

   Book Chapter

   Pages 115-144

   crRNA Biogenesis

   • Emmanuelle Charpentier,
   • John van der Oost,
   • Malcolm F. White
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7. 

   Book Chapter

   Pages 145-169

   Distribution and Mechanism of the Type I CRISPR-Cas Systems

   • Raymond H. J. Staals,
   • Stan J. J. Brouns
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8. 

   Book Chapter

   Pages 171-200

   Type II: Streptococcus thermophilus

   • Marie-Ève Dupuis,
   • Sylvain Moineau
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9. 

   Book Chapter

   Pages 201-219

   Type III CRISPR-Cas Systems and the Roles of CRISPR-Cas in Bacterial Virulence

   • Asma Hatoum-Aslan,
   • Kelli L. Palmer,
   • Michael S. Gilmore
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10. 

    Book Chapter

    Pages 221-250

    CRISPR-Cas Systems to Probe Ecological Diversity and Host–Viral Interactions

    • Nicole L. Held,
    • Lauren M. Childs,
    • Michelle Davison,
    • Joshua S. Weitz
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11. 

    Book Chapter

    Pages 251-266

    Roles of CRISPR in Regulation of Physiological Processes

    • Gil Amitai,
    • Rotem Sorek
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12. 

    Book Chapter

    Pages 267-286

    Applications of the Versatile CRISPR-Cas Systems

    • Philippe Horvath,
    • Giedrius Gasiunas,
    • Virginijus Siksnys
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13. 

    Book Chapter

    Pages 287-291

    CRISPRs in the Microbial Community Context

    • Jillian F. Banfield
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14. Back Matter

    Pages 293-299

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