Overview
- Gives a comprehensive account of the recent advances in anti-malaria drugs
- Chapters contributed by expert authors
- Describes new ideas and directions for study
- Includes supplementary material: sn.pub/extras
Part of the book series: Milestones in Drug Therapy (MDT)
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Table of contents (15 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions.
Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.
Reviews
From the reviews:
“Staines and Krishna successfully captures the essence of what we know about antimalarials at the beginning of the second decade of the 21st century. … the book is a welcome and highly valuable documentation on where we stand and offers valuable food for thought in the search for the way forward.” (Martin P. Grobusch, Trends in Parasitology, September, 2012)
Editors and Affiliations
Bibliographic Information
Book Title: Treatment and Prevention of Malaria
Book Subtitle: Antimalarial Drug Chemistry, Action and Use
Editors: Henry M. Staines, Sanjeev Krishna
Series Title: Milestones in Drug Therapy
DOI: https://doi.org/10.1007/978-3-0346-0480-2
Publisher: Springer Basel
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Basel AG 2012
Hardcover ISBN: 978-3-0346-0479-6Published: 06 January 2012
Softcover ISBN: 978-3-0348-0808-8Published: 22 February 2014
eBook ISBN: 978-3-0346-0480-2Published: 05 January 2012
Series ISSN: 2296-6056
Series E-ISSN: 2296-6064
Edition Number: 1
Number of Pages: X, 318
Topics: Pharmacology/Toxicology, Infectious Diseases, Parasitology, Immunology, Drug Resistance