Editors:
- Covers the details of proteoglycans in all their complexity
- Features lab-ready protocols
- Includes key tips and expert implementation advice to ensure successful results
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 836)
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Table of contents (22 protocols)
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Front Matter
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Proteoglycans
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Front Matter
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Glycosaminoglycans Analysis
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Front Matter
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PGs: Multifunctional Cell Regulators
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Front Matter
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About this book
Now recognized as a reservoir for growth factors and cytokines modulating cell activation status and turnover, proteoglycans have stimulated great amount of interest and research. In Proteoglycans: Methods and Protocols, experts in the field examine issues of basic concepts and up-to-date analysis methods for proteoglycan and glycosaminoglycan (GAG) at the protein and saccharide levels. The volume continues with the multifunctional aspect of proteoglycans, highlighted through three relevant examples of proteoglycans with highly different strucutures: serglycin, aggrecan, and heparin sulphate proteoglycans. The final chapter describes proteoglycan involvement in the pathogenesis of various disorders and their potential therapeutic value in osteo-articular diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and accessible, Proteoglycans: Methods and Protocols is an ideal guide for scientists attempting to pursue further research in this vital and complex area of study.
Editors and Affiliations
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, Faculté de Médicine, INSERM U957 - EA 3822, Nantes, France
Françoise Rédini
Bibliographic Information
Book Title: Proteoglycans
Book Subtitle: Methods and Protocols
Editors: Françoise Rédini
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-498-8
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-61779-497-1Published: 19 January 2012
Softcover ISBN: 978-1-4939-5879-5Published: 23 August 2016
eBook ISBN: 978-1-61779-498-8Published: 19 January 2012
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 359
Topics: Biochemistry, general, Proteomics