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Cancer and IgE

Introducing the Concept of AllergoOncology

  • Book
  • © 2010

Overview

Editors:
  1. Manuel L. Penichet

    1. David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, U.S.A.

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  2. Erika Jensen-Jarolim

    1. Zentrum für Physiologie,, Medizinische Universität Wien, Wien, Austria

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    You can also search for this editor in PubMed   Google Scholar

  • The first volume based on the field named "AllergoOncology"
  • The term "AllergoOncology", recently created by Dr. Jensen-Jarolim, aims to reveal the function of IgE-mediated immune responses against tumor cells in order to enhance the understanding of its biology and develop novel treatment options based on IgE against malignant diseases
  • Includes supplementary material: sn.pub/extras

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-ix
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  2. Introduction

    • Erika Jensen-Jarolim, Manuel L. Penichet
    Pages 1-11

  3. The Biology of IgE: Molecular Mechanism Restraining Potentially Dangerous High Serum IgE Titres In Vivo

    • Gernot Achatz, Gertrude Achatz-Straussberger, Stefan Feichtner, Sebastian Koenigsberger, Stefan Lenz, Doris Peckl-Schmid et al.
    Pages 13-36

  4. The Biology of IgE: The Generation of High-Affinity IgE Antibodies

    • Maria A. Curotto de Lafaille, Juan J. Lafaille
    Pages 37-46

  5. Epidemiological Evidence: IgE, Atopy, and Solid Tumors

    • Michelle C. Turner
    Pages 47-77

  6. Epidemiological Evidence: IgE, Allergies, and Hematopoietic Malignancies

    • Otoniel Martínez-Maza, Alan Duane Moreno, Wendy Cozen
    Pages 79-136

  7. Mast Cells in Allergy and Tumor Disease

    • Anna Wasiuk, Victor C. de Vries, Elizabeth C. Nowak, Randolph J. Noelle
    Pages 137-158

  8. The IgE Antibody and Its Use in Cancer Immunotherapy

    • Tracy R. Daniels, José A. Rodríguez, Elizabeth Ortiz-Sánchez, Gustavo Helguera, Manuel L. Penichet
    Pages 159-183

  9. IgE Interacts with Potent Effector Cells Against Tumors: ADCC and ADCP

    • Sophia N. Karagiannis, Frank O. Nestle, Hannah J. Gould
    Pages 185-213

  10. IgE as Adjuvant in Tumor Vaccination

    • Elisa A. Nigro, Antonio G. Siccardi, Luca Vangelista
    Pages 215-229

  11. The Targets of IgE: Allergen-Associated and Tumor-Associated Molecular Patterns

    • Erika Jensen-Jarolim, Diana Mechtcheriakova, Isabella Pali-Schoell
    Pages 231-254

  12. The Role of Th2-Mediated Anti-Tumor Immunity in Tumor Surveillance and Clearance

    • Ljubov Simson, Julia I. Ellyard, Christopher R. Parish
    Pages 255-275

  13. Back Matter

    Pages 277-287
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Keywords

About this book

Erika Jensen-Jarolim and Manuel L. Penichet 1. 1 Background Infectious diseases, being the major burden in the history of mankind worldwide th until the beginning of the 20 century, were important triggers in the understanding of immunological mechanisms. In contrast to infectious diseases, reports of all- gies and cancers were less common, but increased tremendously within the last century. Based on the US mortality data of the National Center for Health Statistics, Centers for Disease Control and Prevention 2009, a recent report from the American Cancer Society indicated that the number of cancer deaths increased approximately from 100,000 to 550,000 per year between 1930 and 2006, paralleling the increase of the total population during this period. Leading causes of death from cancer are lung and bronchus cancer, in men prostate cancer, and in women breast c- cer [1, 2]. Normalization to population size shows that the cancer death rate for most malignancies has been generally stable, although the mortality rate of certain malignancies, such as lung and bronchus cancer, has increased over the last 50 years [1-3]. In allergy, the situation is less clear, because for the time period around the turn of th the 19 century, only imprecise information is available. However, within the last 30 years the incidences of allergies has doubled not only in industrial countries, but in developing countries as well [4].

Reviews

From the reviews:

“The book begins by giving a brief description of the long history of observations and research … into the existence of a negative correlation between the frequency of allergies and the incidence of cancer, as well as a history of allergy research in general. … the new concept of AllergoOncology, as introduced in this book, is a provocative one … . a well-written and presented book introducing a new concept in cancer immunology, as well as a comprehensive description of IgE biology in general.” (Andrew T. Vaughan, Immunology News, February, 2011)

“This book represents a description of how IgE antibodies may play a role protecting against cancer development and progression. … The audience for this book includes oncologists, allergists, and researchers, as well as students and fellows. It has a place in any health sciences library. … It is well written and full of thoughtful points and it would be a useful addition to the library of an educational institution or to the laboratory of researchers interested in this topic.” (Marion C. Cohen, Doody’s Review Service, July, 2010)

Editors and Affiliations

  • David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, U.S.A.

    Manuel L. Penichet

  • Zentrum für Physiologie,, Medizinische Universität Wien, Wien, Austria

    Erika Jensen-Jarolim

Bibliographic Information

  • Book Title: Cancer and IgE

  • Book Subtitle: Introducing the Concept of AllergoOncology

  • Editors: Manuel L. Penichet, Erika Jensen-Jarolim

  • DOI: https://doi.org/10.1007/978-1-60761-451-7

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Humana Press 2010

  • Hardcover ISBN: 978-1-60761-450-0Published: 04 March 2010

  • Softcover ISBN: 978-1-62703-852-2Published: 21 September 2014

  • eBook ISBN: 978-1-60761-451-7Published: 23 January 2010

  • Edition Number: 1

  • Number of Pages: IX, 287

  • Topics: Cancer Research, Immunology, Oncology

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