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Molecular Profiling

Methods and Protocols

  • Book
  • © 2012

Overview

  • Emphasis placed on tissue based molecular profiling not covered in pathology text books
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 823)

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Table of contents (28 protocols)

Keywords

About this book

The next revolution in molecular medicine is the application of molecular profiling to individualized patient therapy. Molecular profiling technology has advanced dramatically, particularly in the field of cancer tissue biomarkers. It is now possible to gather complex genomic and proteomic information from a routine clinical needle biopsy or surgical specimen. In Molecular Profiling : Methods and Protocols, expert researchers in the field focus on the entire process from discovery to commercialization, with practical guides that are not limited to experimental methods. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, as well as essays and guidelines for grants, patents, and commercialization of products related to molecular profiling.


 Authoritative and practical, Molecular Profiling: Methods and Protocols seeks to aid scientists in understanding the latest advancements in genomics, proteomics, imagining, and bioinformatics.

Reviews

From the reviews:

“This informative book combines genomics, proteomics, and bioinformatics with experimental protocols and detailed discussions regarding future challenges in commercialization and practical use in the field with an emphasis on tissue-based molecular profiling. … readers can use this as a practical guide at the laboratory bench as well as in the boardroom. The book is written for scientists, pathologists, oncologists, biotechnologists, residents, medical students, and nurses involved in clinical trial research. … This will be a valuable tool for those involved in clinical trial research.” (Omer Iqbal, Doody’s Book Reviews, April, 2012)

Editors and Affiliations

  • Center for Applied Proteomics and, George Mason University, Manassas, USA

    Virginia Espina

  • Center for Applied Proteomics &, George Mason University, Manassas, USA

    Lance A. Liotta

Bibliographic Information

  • Book Title: Molecular Profiling

  • Book Subtitle: Methods and Protocols

  • Editors: Virginia Espina, Lance A. Liotta

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-60327-216-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-60327-215-5Published: 12 November 2011

  • Softcover ISBN: 978-1-4939-5684-5Published: 23 August 2016

  • eBook ISBN: 978-1-60327-216-2Published: 13 November 2011

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XIII, 447

  • Topics: Molecular Medicine, Pathology

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