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  • © 2013

Primates, Pathogens, and Evolution

  • Integrates research from a broad range of fields on primate-pathogen molecular interactions, primate immune function, and primate-pathogen co-evolution
  • Provides a sound base of knowledge for future investigation of human and non-human primate evolution, immunity, and disease
  • Allows the specialist and educated lay-reader to understand and critically evaluate current data on differences in the molecular mechanics of primate immune response, pathogen-mediated primate evolution, and primate health

Part of the book series: Developments in Primatology: Progress and Prospects (DIPR, volume 38)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-x
  2. Primates, Pathogens and Evolution: An Introduction

    • Jessica F. Brinkworth, Kate Pechenkina
    Pages 1-14
  3. Immunity and Primate Evolution

    1. Front Matter

      Pages 15-15
    2. Vertebrate Immune System Evolution and Comparative Primate Immunity

      • Jessica F. Brinkworth, Mitchell Thorn
      Pages 17-64
    3. Toll-Like Receptor Function and Evolution in Primates

      • Jessica F. Brinkworth, Kirstin N. Sterner
      Pages 91-116
    4. Impact of Natural Selection Due to Malarial Disease on Human Genetic Variation

      • Felicia Gomez, Wen-Ya Ko, Avery Davis, Sarah A. Tishkoff
      Pages 117-160
    5. Parasitic Lice Help to Fill in the Gaps of Early Hominid History

      • Julie M. Allen, Cedric O. Worman, Jessica E. Light, David L. Reed
      Pages 161-186
  4. Emergence and Divergent Disease Manifestation

    1. Front Matter

      Pages 187-187
    2. Molecular Mimicry by γ-2 Herpesviruses to Modulate Host Cell Signaling Pathways

      • Lai-Yee Wong, Zsolt Toth, Kevin F. Brulois, Kyung-Soo Inn, Sun Hwa Lee, Hye-Ra Lee et al.
      Pages 221-251
    3. Neotropical Primates and Their Susceptibility to Toxoplasma gondii: New Insights for an Old Problem

      • José Luiz Catão-Dias, Sabrina Epiphanio, Maria Cecília Martins Kierulff
      Pages 253-289
    4. The Evolution of SIV in Primates and the Emergence of the Pathogen of AIDS

      • Edward J. D. Greenwood, Fabian Schmidt, Jonathan L. Heeney
      Pages 291-327
  5. Primates, Pathogens and Health

    1. Front Matter

      Pages 329-329
    2. Make New Friends and Keep the Old? Parasite Coinfection and Comorbidity in Homo sapiens

      • Melanie Martin, Aaron D. Blackwell, Michael Gurven, Hillard Kaplan
      Pages 363-387
    3. Primates, Pathogens, and Evolution: A Context for Understanding Emerging Disease

      • Kristin N. Harper, Molly K. Zuckerman, Bethany L. Turner, George J. Armelagos
      Pages 389-409
  6. Back Matter

    Pages 411-428

About this book

The immune systems of human and non-human primates have diverged over time, such that some species differ considerably in their susceptibility, symptoms, and survival of particular infectious diseases. Variation in primate immunity is such that major human pathogens - such as immunodeficiency viruses, herpesviruses and malaria-inducing species of Plasmodium - elicit striking differences in immune response between closely related species and within primate populations. These differences in immunity are the outcome of complex evolutionary processes that include interactions between the host, its pathogens and symbiont/commensal organisms. The success of some pathogens in establishing persistent infections in humans and other primates has been determined not just by the molecular evolution of the pathogen and its interactions with the host, but also by the evolution of primate behavior and ecology, microflora, immune factors and the evolution of other biological systems.

To explore how interactions between primates and their pathogens have shaped their mutual molecular evolution, Primates, Pathogens and Evolution brings together research that explores comparative primate immune function, the emergence of major and neglected primate diseases, primate-microorganism molecular interactions, and related topics. This book will be of interest to anyone curious as to why infectious diseases manifest differently in humans and their closest relatives. It will be of particular interest to scholars specializing in human and non-human primate evolution, epidemiology and immunology, and disease ecology. Primates, Pathogens and Evolution offers an overview and discussion of current findings on differences in the molecular mechanics of primate immune response, as well as on pathogen-mediated primate evolution and human and non-human primate health.

Editors and Affiliations

  • Department of Pediatrics, CHU Saint-Justine Research Center, University of Montreal, Montreal, QC, Canada

    Jessica F. Brinkworth

  • Department of Anthropology, Queens College, City University of New Y, New York, USA

    Kate Pechenkina

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access