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  • Book
  • © 2013

Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines

Editors:

  1. Manmohan Singh

    1. Novartis Vaccines Research, Cambridge, USA

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  • Focus on the future of vaccines
  • Addresss delivery systems for vaccines
  • Explore the use of nanoparticles in vaccine delivery?

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-x
    PDF

  2. Novel Immune Potentiators and Delivery Systems for Enhancing Vaccine Potency

    1. Front Matter

      Pages 1-1
      PDF

  3. Novel Immune Potentiators and delivery systems for enhancing vaccine potency

    1. TLR7/8 Agonists as Vaccine Adjuvants

      • Mark A. Tomai, John P. Vasilakos
      Pages 3-18

    2. Preclinical and Clinical Development of Synthetic iNKT-Cell Glycolipid Agonists as Vaccine Adjuvants

      • Josianne Nitcheu, Sandrine Crabe, Gwyn Davies, Vincent Serra
      Pages 19-64

    3. Mucosal Vaccination: Opportunities and Challenges

      • Olga Borges, Gerrit Borchard
      Pages 65-80

    4. Oral Vaccination: Attenuated and Gene-Based

      • Wendy Peters, Ciaran D. Scallan, Sean N. Tucker
      Pages 81-104

  4. Design and Development of Next Generation Vaccines

    1. Front Matter

      Pages 105-105
      PDF

  5. Design and Development of next generation vaccines

    2. High Throughput Screening for Stabilizers of Vaccine Antigens

      • C. Russell Middaugh, David B. Volkin, Sangeeta B. Joshi
      Pages 119-143

  6. Novel Delivery Technologies for Vaccines

    1. Front Matter

      Pages 183-183
      PDF

  7. Novel Delivery Technologies for vaccines

    1. Current Status of Electroporation Technologies for Vaccine Delivery

      • Claire F. Evans, Drew Hannaman
      Pages 185-215

    4. Mimopath™-Based Vaccine Delivery

      • Kees Leenhouts
      Pages 245-265

  8. Novel Particulate Delivery Systems for Vaccines and Adjuvants

    1. Front Matter

      Pages 267-267
      PDF

  9. Novel Particulate delivery systems for vaccines and adjuvants

    1. NanoBio™ Nanoemulsion for Mucosal Vaccine Delivery

      • Tarek Hamouda, Jakub Simon, Ali Fattom, James Baker
      Pages 269-286

    2. Influenza Virosomes as Antigen Delivery System

      • Christian Moser, Mario Amacker
      Pages 287-307

    3. Matrix M Adjuvant Technology

      • Karin Lövgren Bengtsson
      Pages 309-320
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About this book

Development of new-generation vaccines is now more challenging than ever, as identifying, purifying and evaluating vaccine antigens is a complex undertaking. Most importantly, once the relevant antigens have been identified, key focus then shifts to the development of suitable delivery systems and formulations to achieve maximum in vivo potency with minimum potential side effects. These novel formulations—many of which will be nanoparticulates—can deliver the antigens to the desired site, to the relevant antigen presenting cells, and prevent systemic exposure of the immune potentiators. The proposed book will outline all the critical steps that need to be considered for successful development of various types of nanoparticulate delivery systems for vaccine antigens. These contributions from leading experts in the area of vaccine formulation and delivery systems will tie in what is the most current status, including clinical evaluations with these novel vaccine technologies.​
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Keywords

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Editors and Affiliations

  • Novartis Vaccines Research, Cambridge, USA

    Manmohan Singh

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Bibliographic Information

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Access via your institution

Buy it now

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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