Editors:
It will describe the most common methods used in animal models of bone research.
This book will provide some detailed protocols for sample acquisition and manipulation, data obtention and data interpretation.
Techniques such as bone histomorphometry, microCT and ex vivo cultures will be described in detail.
A clear distinction between animal models for postmenopausal and senile osteoporosis is made in this book. This distinction will provide the reader with a better and more appropriate selection when testing treatments in animal models of menopausal vs. senile osteoporosis.
This book will be especially useful to bone biologists and gerontologists.
Differences between methodologies when looking at hormonal effect versus the aging process will be highlighted and will provide the reader with a better understanding of the model and their expected results.
Includes supplementary material: sn.pub/extras
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Table of contents (14 chapters)
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Front Matter
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Back Matter
About this book
Osteoporosis Research - Animal Models, presents in a very illustrative and practical manner, general methodologies of bone studies in animals, as well as the particular features of the most commonly used animal models in the field.
Research in the field of osteoporosis has grown in recent years. This has resulted in significant advances in determining the causes of osteoporosis, assessing risk factors, and creating new treatment methods. The use of animal models provides important knowledge about pathological conditions that can eventually lead to the development of more effective clinical treatment of diseases in both humans and animals. Â
Osteoporosis Research - Animal Models, is an essential tool for researchers in the bone field. This book aids researchers in selecting their appropriate model and highlights the experiments that can be strategically designed to optimize the potential of an animal to develop the cardinal features of osteoporosis in humans. This book addresses the importance of recent findings from animal models and their significance on the pathogenesis of osteoporosis in relation to human disease.
Editors and Affiliations
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Nepean Hospital, Dept. Geriatric Medicine, University of Sydney, Penrith, Australia
Gustavo Duque
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Department of Bone & Joint Disease, National Center for Geriatrics & Geronto, Obu-Aichi, Japan
Ken Watanabe
Bibliographic Information
Book Title: Osteoporosis Research
Book Subtitle: Animal Models
Editors: Gustavo Duque, Ken Watanabe
DOI: https://doi.org/10.1007/978-0-85729-293-3
Publisher: Springer London
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag London Limited 2011
Hardcover ISBN: 978-0-85729-292-6Published: 25 May 2011
Softcover ISBN: 978-1-4471-6229-2Published: 20 August 2014
eBook ISBN: 978-0-85729-293-3Published: 23 May 2011
Edition Number: 1
Number of Pages: XIX, 196
Topics: Endocrinology, Orthopedics, Biomedicine general