Table of contents (22 chapters)

1. Front Matter

   Pages i-xix

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2. Introduction and Historical Perspective

   1. 

      Book Chapter

      Pages 1-5

      Introduction and Historical Perspective

      • Peter Gunning
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3. Genes and Their Expression

   1. 

      Book Chapter

      Pages 6-26

      Structure and Evolution of Tropomyosin Genes

      • Bernadette Vrhovski,
      • Nadine Thézé,
      • Pierre Thiébaud
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   2. 

      Book Chapter

      Pages 27-42

      Tropomyosin Exons as Models for Alternative Splicing

      • Clare Gooding,
      • Christopher W. J. Smith
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   3. 

      Book Chapter

      Pages 43-59

      Tropomyosin Gene Expression in Vivo and in Vitro

      • Galina Schevzov,
      • Geraldine O’Neill
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4. Protein Structure

   1. 

      Book Chapter

      Pages 60-72

      Tropomyosin: Function Follows Structure

      • Sarah E. Hitchcock-DeGregori
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   2. 

      Book Chapter

      Pages 73-84

      Dimerization of Tropomyosins

      • Mario Gimona
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5. Role in Muscle Function

   1. 

      Book Chapter

      Pages 85-94

      Cooperative Binding of Tropomyosin to Actin

      • Larry S. Tobacman
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   2. 

      Book Chapter

      Pages 95-109

      Tropomyosin and the Steric Mechanism of Muscle Regulation

      • William Lehman,
      • Roger Craig
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   3. 

      Book Chapter

      Pages 110-123

      Role of Tropomyosin in the Regulation of Contraction in Smooth Muscle

      • Steve Marston,
      • M. El-Mezgueldi
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6. Tropomyosin in Human Disease

   1. 

      Book Chapter

      Pages 124-131

      Tropomyosin as a Regulator of Cancer Cell Transformation

      • David M. Helfman,
      • Patrick Flynn,
      • Protiti Khan,
      • Ali Saeed
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   2. 

      Book Chapter

      Pages 132-142

      The Role of Tropomyosin in Heart Disease

      • David F. Wieczorek,
      • Ganapathy Jagatheesan,
      • Sudarsan Rajan
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   3. 

      Book Chapter

      Pages 143-157

      Tropomyosins in Skeletal Muscle Diseases

      • Anthony J. Kee,
      • Edna C. Hardeman
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   4. 

      Book Chapter

      Pages 158-167

      Tropomyosins in Human Diseases: Ulcerative Colitis

      • Kiron M. Das,
      • Manisha Bajpai
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7. Tropomyosin Directed Regulation of the Cytoskeleton

   1. 

      Book Chapter

      Pages 168-186

      Tropomyosin Function in Yeast

      • David Pruyne
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   2. 

      Book Chapter

      Pages 187-200

      Isoform Sorting of Tropomyosins

      • Claire Martin,
      • Peter Gunning
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   3. 

      Book Chapter

      Pages 201-222

      Human Tropomyosin Isoforms in the Regulation of Cytoskeleton Functions

      • Jim Jung-Ching Lin,
      • Robbin D. Eppinga,
      • Kerri S. Warren,
      • Keith R. McCrae
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8. Mechanisms of Tropomyosin Function

   1. 

      Book Chapter

      Pages 223-231

      Tropomyosins Regulate the Impact of Actin Binding Proteins on Actin Filaments

      • Uno Lindberg,
      • Clarence E. Schutt,
      • Robert D. Goldman,
      • Maria Nyåkern-Meazza
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   2. 

      Book Chapter

      Pages 232-249

      Tropomyosin and ADF/Cofilin as Collaborators and Competitors

      • Thomas B. Kuhn,
      • James R. Bamburg
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   3. 

      Book Chapter

      Pages 250-272

      Caldesmon and the Regulation of Cytoskeletal Functions

      • C. -L. Albert Wang
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   4. 

      Book Chapter

      Pages 273-282

      Tropomyosins as Discriminators of Myosin Function

      • E. Michael Ostap
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