ISBN: 978-0-387-85765-7 (Print) 978-0-387-85766-4 (Online)
Download Book (15,724 KB) As a courtesy to our readers the eBook is provided DRM-free. However, please note that Springer uses effective methods and state-of-the art technology to detect, stop, and prosecute illegal sharing to safeguard our authors’ interests.

Table of contents (22 chapters)

previous Page of 2
  1. Front Matter

    Pages i-xix

  2. Introduction and Historical Perspective

    1. Book Chapter

      Pages 1-5

      Introduction and Historical Perspective

  3. Genes and Their Expression

    1. Book Chapter

      Pages 6-26

      Structure and Evolution of Tropomyosin Genes

    2. Book Chapter

      Pages 27-42

      Tropomyosin Exons as Models for Alternative Splicing

    3. Book Chapter

      Pages 43-59

      Tropomyosin Gene Expression in Vivo and in Vitro

  4. Protein Structure

    1. Book Chapter

      Pages 60-72

      Tropomyosin: Function Follows Structure

    2. Book Chapter

      Pages 73-84

      Dimerization of Tropomyosins

  5. Role in Muscle Function

    1. Book Chapter

      Pages 85-94

      Cooperative Binding of Tropomyosin to Actin

    2. Book Chapter

      Pages 95-109

      Tropomyosin and the Steric Mechanism of Muscle Regulation

    3. Book Chapter

      Pages 110-123

      Role of Tropomyosin in the Regulation of Contraction in Smooth Muscle

  6. Tropomyosin in Human Disease

    1. Book Chapter

      Pages 124-131

      Tropomyosin as a Regulator of Cancer Cell Transformation

    2. Book Chapter

      Pages 132-142

      The Role of Tropomyosin in Heart Disease

    3. Book Chapter

      Pages 143-157

      Tropomyosins in Skeletal Muscle Diseases

    4. Book Chapter

      Pages 158-167

      Tropomyosins in Human Diseases: Ulcerative Colitis

  7. Tropomyosin Directed Regulation of the Cytoskeleton

    1. Book Chapter

      Pages 168-186

      Tropomyosin Function in Yeast

    2. Book Chapter

      Pages 187-200

      Isoform Sorting of Tropomyosins

    3. Book Chapter

      Pages 201-222

      Human Tropomyosin Isoforms in the Regulation of Cytoskeleton Functions

  8. Mechanisms of Tropomyosin Function

    1. Book Chapter

      Pages 223-231

      Tropomyosins Regulate the Impact of Actin Binding Proteins on Actin Filaments

    2. Book Chapter

      Pages 232-249

      Tropomyosin and ADF/Cofilin as Collaborators and Competitors

    3. Book Chapter

      Pages 250-272

      Caldesmon and the Regulation of Cytoskeletal Functions

    4. Book Chapter

      Pages 273-282

      Tropomyosins as Discriminators of Myosin Function

previous Page of 2