New Mechanisms for Tissue-Selective Estrogen-Free Contraception

  • H. B. Croxatto
  • R. Schürmann
  • U. Fuhrmann
  • I. Schellschmidt
Conference proceedings

DOI: 10.1007/b138677

Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 52)

Table of contents (11 papers)

  1. Front Matter
    Pages I-XII
  2. Reproductive Tissue-Selective Actions of Progesterone Receptors
    B. Mulac-Jericevic, O. M. Conneely
    Pages 19-37
  3. The Progesterone Receptor/Estradiol Receptor Association and the Progestin-Triggered S-Phase Entry
    A. Migliaccio, G. Castoria, M. Di Domenico, C. Ballaré, M. Beato, F. Auricchio
    Pages 39-54
  4. Endometrial Morphology and Progestogens
    H. O. D. Critchley
    Pages 55-88
  5. Effects of Progestogens on Endometrial Maturation in the Implantation Phase
    K. Gemzell-Danielsson, M. Bygdeman
    Pages 119-138
  6. Gene Expression During the Implantation Window: Microarray Analysis of Human Endometrial Samples
    A. Schmidt, P. Groth, B. Haendler, H. Hess-Stumpp, J. Krätzschmar, H. Seidel et al.
    Pages 139-157
  7. Human Endocervical Mucins
    I. K. Gipson
    Pages 219-244
  8. Back Matter
    Pages 263-266

About these proceedings


Combined oral contraceptives are the most convenient and accepted method of hormonal contraception. Nevertheless, the medical community and consumers constantly demand innovation, additional benefits during use and lower hormonal load despite the high safety profile of available products. At the Ernst Schering Research Foundation Workshop 52, new perspectives and mechanisms for tissue-selective, estrogen-free contraception were discussed. The aim of the workshop was to bring together experts in the field of molecular and pharmacodynamic action of progestins with clinicians and medical experts to discuss potential medical endpoints, physiological reactions and (bio)marker useful describing the tissue selectivity and the contraceptive action of new progestins in different target organs. A major factor for successful realization of these new concepts is a deeper understanding of local pharmacological responses to progestins in general and to new progestins in particular.


Contraception Embryo Hormone Progestin Progestogen

Editors and affiliations

  • H. B. Croxatto
    • 1
  • R. Schürmann
    • 2
  • U. Fuhrmann
    • 3
  • I. Schellschmidt
    • 2
  1. 1.Instituto Chileno de Medicina Reproductive (ICMER)Santiago de ChileChile
  2. 2.Strategic Business Unit, Gynecology and AndrologySchering AGBerlinGermany
  3. 3.CRBA, Gynecology and Andrology, Female Health CareSchering AGBerlinGermany

Bibliographic information

  • Copyright Information Springer-Verlag Berlin Heidelberg 2005
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-540-23089-2
  • Online ISBN 978-3-540-27147-5
  • Series Print ISSN 0947-6075