The Biology and Pathology of Innate Immunity Mechanisms

Editors:

ISBN: 978-0-306-46409-6 (Print) 978-0-306-46831-5 (Online)

Table of contents (25 chapters)

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  1. Pattern Recognition, Receptors and Collectins in Innate Immunity

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      Pages 1-14

      Mannose Receptor and Scavenger Receptor: Two Macrophage Pattern Recognition Receptors with Diverse Functions in Tissue Homeostasis and Host Defense

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      Pages 15-25

      Complement Receptor 3 (CR3): A Public Transducer of Innate Immunity Signals in Macrophages

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      Pages 27-36

      The Role of C-type Lectins in the Innate Immunity Against Pulmonary Pathogens

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      Pages 37-48

      Modulation of Nitric Oxide Production by Lung Surfactant in Alveolar Macrophages

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      Pages 49-59

      Development of Chimeric Collectins with Enhanced Activity Against Influenza a Virus

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      Pages 61-71

      Initial Steps in Streptococcus pneumoniae Interaction with and Pathogenicity to the Host

  2. Host Cells and Cytokinesin Innate Immunity

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      Pages 73-89

      Role of Cytokines in the Maturation and Function of Macrophages

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      Pages 91-105

      Mast Cell Modulation of the Innate Immune Response to Enterobacterial Infection

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      Pages 107-114

      The Nadph Oxidase Diaphorase Activity in Permeabilized Human Neutrophils and Granulocytic Like PLB-985 Cells

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      Pages 115-123

      Activation of Cytosolic Phospholipase A2 by Opsonized Zymosan in Human Neutrophils Requires Both ERK and p38 Map-Kinase

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      Pages 125-135

      Cytosolic Phospholipase A2 is Required for the Activation of the Nadph Oxidase Associated H+ Channel in Phagocyte-Like Cells

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      Pages 137-145

      The Role of NK Cells in Innate Immunity

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      Pages 147-161

      Similarities and Dissimilarities Between Humans and Mice Looking at Adhesion Molecules Defects

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      Pages 163-173

      The Role of Dendritic Cells at the Early Stages of Leishmania Infection

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      Pages 175-184

      DNA-Based Vaccines: Role of Dendritic Cells in Antigen Presentation

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      Pages 185-202

      Distinct Patterns of IL-Lα and IL-Lβ Organ Distribution-A Possible Basis for Organ Mechanisms of Innate Immunity

  3. Antimicrobial Peptides

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      Pages 203-218

      Structure and Biology of Cathelicidins

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      Pages 219-222

      Structure Activity Relationship Study of Polymyxin B Nonapeptide

  4. Innate Immunity in the Compromised Host

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      Pages 223-225

      The Clinical Significance of Neutrophil Dysfunction

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      Pages 227-235

      Clinical Significance of Functional Aberrations in Macrophage and NK Cells, in Type-1 Cytokines and in Lectin-Binding Molecules

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