Sliding Filament Mechanism in Muscle Contraction

Fifty Years of Research

Editors:

ISBN: 978-0-387-24989-6 (Print) 978-0-387-24990-2 (Online)

Table of contents (33 chapters)

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  1. Sliding Filament Mechanism at the Molecular Level

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-11

      Early Developments in Muscle Research and the Role of New Structural Technologies

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      Book Chapter

      Pages 13-23

      The Molecular Basis of Cross-Bridge Function

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      Book Chapter

      Pages 25-36

      Molecular Synchronization in Actomyosin Motors — From Single Molecule to Muscle Fiber Via Nanomuscle

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      Book Chapter

      Pages 37-44

      Distribution of Crossbridge States in Contracting Muscle

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      Book Chapter

      Pages 45-60

      X-Ray Diffraction Studies of Striated Muscles

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      Book Chapter

      Pages 61-72

      Conformational Change and Regulation of Myosin Molecules

  2. Mechanism of Muscle Contraction

    1. Front Matter

      Pages 73-73

    2. No Access

      Book Chapter

      Pages 75-91

      Driving Filament Sliding: Weak binding cross-bridge states, strong binding cross-bridge states, and the power stroke

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      Book Chapter

      Pages 93-112

      Mysteries about Amplitude and Efficiency of Cross-Bridge Powerstroke

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      Book Chapter

      Pages 113-126

      Sarcomere Dynamics, Stepwise Shortening and the Nature of Contraction

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      Book Chapter

      Pages 127-140

      Crossbridge Formation Detected by Stiffness Measurements in Single Muscle Fibres

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      Book Chapter

      Pages 141-155

      Non Cross-Bridge Stiffness in Skeletal Muscle Fibres at Rest and During Activity

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      Book Chapter

      Pages 157-167

      Nature’s Strategy for Optimizing Power Generation in Insect Flight Muscle

  3. Muscle Energetics

    1. Front Matter

      Pages 169-169

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      Book Chapter

      Pages 171-182

      From Crossbridges to Metabolism: System Biology for Energetics

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      Book Chapter

      Pages 183-192

      Energetics, Mechanics and Molecular Engineering of Calcium Cycling in Skeletal Muscle

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      Book Chapter

      Pages 193-203

      Heat, Phosphorus NMR and Microcalorimetry in Relation to the Mechanism of Filament Sliding

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      Book Chapter

      Pages 205-219

      How Two-Foot Molecular Motors May Walk

  4. Regulatory Mechanism and E-C Coupling

    1. Front Matter

      Pages 221-221

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      Book Chapter

      Pages 223-231

      Molecular Basis of Calcium Regulation of Striated Muscle Contraction

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      Book Chapter

      Pages 233-247

      Mechanisms of Calcium Release from the Sarcoplasmic Reticulum in Skeletal Muscle

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      Book Chapter

      Pages 249-265

      From Inward Spread of Activation, Active Elongation to the Effect of Organic Calcium Channel Blockers in Muscle Excitation-Contraction Coupling

  5. Cardiac and Smooth Muscle

    1. Front Matter

      Pages 267-267

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      Book Chapter

      Pages 269-282

      Cardiac Myosin Binding Protein C: Modulator of Contractility

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