2005

Molecular Autoimmunity

Editors:

ISBN: 978-0-387-24533-1 (Print) 978-0-387-24534-8 (Online)

Table of contents (28 chapters)

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  1. Front Matter

    Pages i-xxvii

  2. Innate Immunity in Autoimmune Diseases

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      Book Chapter

      Pages 1-15

      Innate Immunity in Experimental Autoimmune Myocarditis

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      Book Chapter

      Pages 17-25

      Toll-like Receptor 9 and Autoimmunity

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      Book Chapter

      Pages 27-41

      C-Reactive Protein as a Regulator of Autoimmune Disease

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      Book Chapter

      Pages 43-53

      NKT Cells and Autoimmune Type 1 Diabetes

  3. Genetics of Autoimmune Diseases

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      Book Chapter

      Pages 55-67

      The Genetics of Human Autoimmune Diseases

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      Book Chapter

      Pages 69-83

      Failure to Maintain T Cell DNA Methylation and Chromatin Structure Contributes to Human Lupus

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      Book Chapter

      Pages 85-99

      Complement Components C4A and C4B in Human Lupus

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      Book Chapter

      Pages 101-113

      Non-MHC Genetic Polymorphisms with Functional Importance for Human Myasthenia Gravis

  4. Triggers of the Autoimmune Attack

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      Book Chapter

      Pages 115-125

      Rheumatic Heart Disease: Molecular Basis of Autoimmune Reactions Leading to Valvular Lesions

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      Book Chapter

      Pages 127-139

      Autoimmunity against Desmogleins in Pemphigus Vulgaris

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      Book Chapter

      Pages 141-150

      The Molecular Basis of Celiac Disease

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      Book Chapter

      Pages 151-164

      Intrathymic Expression of Neuromuscular Acetylcholine Receptors and the Immunopathogenesis of Myasthenia Gravis

  5. Targets of the Autoimmune Attack

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      Book Chapter

      Pages 165-180

      Autoantibodies and Nephritis: Different Roads May Lead to Rome

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      Book Chapter

      Pages 181-196

      Estrogen, Interferon-gamma, and Lupus

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      Book Chapter

      Pages 197-208

      Extent of Regulatory T Cell Influence on Major Histocompatibility Complex Class II Gene Control of Susceptibility in Murine Autoimmune Thyroiditis

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      Book Chapter

      Pages 209-225

      The Role of Autoimmunity in Multiple Sclerosis

  6. Immune Receptor Signaling Pathways

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      Book Chapter

      Pages 227-243

      Crippled B Lymphocyte Signaling Checkpoints in Systemic Autoimmunity

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      Book Chapter

      Pages 245-261

      Disrupted T Cell Receptor Signaling Pathways in Systemic Autoimmunity

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      Book Chapter

      Pages 263-278

      Immune Cell Signaling and Gene Transcription in Human Systemic Lupus Erythematosus

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      Book Chapter

      Pages 279-289

      Accumulation of Self-Antigens in Systemic Lupus Erythematosus

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