Molecular Targeting and Signal Transduction

Editors:

ISBN: 978-1-4020-7822-4 (Print) 978-1-4020-7847-7 (Online)

Table of contents (15 chapters)

  1. No Access

    Book Chapter

    Pages 1-13

    Biology of the Epidermal Growth Factor Receptor Family

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    Book Chapter

    Pages 15-31

    Integrin Signaling in Cancer

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    Book Chapter

    Pages 33-58

    Regulators of Vascular Endothelial Growth Factor Expression in Cancer

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    Book Chapter

    Pages 59-75

    Integrin-Linked Kinase (ILK) in Combination Molecular Targeting

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    Book Chapter

    Pages 77-88

    P21-Activated Kinase 1: An Emerging Therapeutic Target

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    Book Chapter

    Pages 89-119

    Basis and Importance of SRC as a Target in Cancer

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    Book Chapter

    Pages 121-138

    Therapeutic Targeting of the Receptor Tyrosine Kinase Met

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    Book Chapter

    Pages 139-173

    Nuclear Factor-κB Activation Mediates Cellular Transformation, Proliferation, Invasion Angiogenesis and Metastasis of Cancer

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    Book Chapter

    Pages 175-181

    The P53 Pathway: Targets for the Development of Novel Cancer Therapeutics

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    Book Chapter

    Pages 189-215

    Runx Protein Signaling in Human Cancers

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    Book Chapter

    Pages 217-237

    Signal Transduction Mediated by Cyclin D1: from Mitogens to Cell Proliferation: A Molecular Target with Therapeutic Potential

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    Book Chapter

    Pages 239-270

    Signal Transduction Pathways in BCR-ABL Transformed Cells

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    Book Chapter

    Pages 271-292

    Estrogen Receptors and Anti-Estrogen Therapies

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    Book Chapter

    Pages 293-314

    Targeting Endothelin Axis in Cancer

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    Book Chapter

    Pages 315-327

    km23: A Novel TGFβ Signaling Target Altered in Ovarian Cancer