2005

Neurodegeneration and Prion Disease

Editors:

ISBN: 978-0-387-23922-4 (Print) 978-0-387-23923-1 (Online)

Table of contents (17 chapters)

  1. No Access

    Book Chapter

    Pages 1-11

    Introduction

  2. No Access

    Book Chapter

    Pages 13-48

    Neuropathology of Transmissible Spongiform Encephalopathies (Prion Diseases)

  3. No Access

    Book Chapter

    Pages 49-82

    Central Pathogenesis of Prion Diseases

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    Book Chapter

    Pages 83-109

    Hereditary Prion Protein Amyloidoses

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    Book Chapter

    Pages 111-137

    Mouse Behavioural Studies and What They Can Teach Us about Prion Diseases

  6. No Access

    Book Chapter

    Pages 139-165

    Electrophysiological Approaches to the Study of Prion Diseases

  7. No Access

    Book Chapter

    Pages 167-193

    Prion Protein, Prion Protein-Like Protein, and Neurodegeneration

  8. No Access

    Book Chapter

    Pages 195-216

    Oxidative Stress and Mitochondrial Dysfunction in Neurodegeneration of Transmissible Spongiform Encephalopathies (TSEs)

  9. No Access

    Book Chapter

    Pages 217-240

    Mechanisms of Prion Toxicity and Their Relationship to Prion Infectivity

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    Book Chapter

    Pages 241-271

    A Stone Guest on the Brain: Death as a Prion

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    Book Chapter

    Pages 273-297

    Molecular Mechanisms Mediating Neuronal Cell Death in Experimental Models of Prion Diseases, in vitro

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    Book Chapter

    Pages 299-318

    Processing and Mis-Processing of the Prion Protein: Insights into the Pathogenesis of Familial Prion Disorders

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    Book Chapter

    Pages 319-344

    Signaling Pathways Controling Prion Neurotoxicity: Role of Endoplasmic Reticulum Stress-Mediated Apoptosis

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    Book Chapter

    Pages 345-378

    Cell Culture Models to Unravel Prion Protein Function and Aberrancies in TSE

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    Book Chapter

    Pages 379-405

    Insights into the Cellular Trafficking of Prion Proteins

  16. No Access

    Book Chapter

    Pages 407-450

    The Molecular Basis of Prion Protein-Mediated Neuronal Damage

  17. No Access

    Book Chapter

    Pages 451-456

    Conclusion: Intervention, the Final Frontier