2013

Prostate Cancer: Shifting from Morphology to Biology

Editors:

ISBN: 978-94-007-7148-2 (Print) 978-94-007-7149-9 (Online)

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xviii

  2. Clues to Morphological Diagnosis and Prognosis Evaluation

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-42

      Update on Diagnostic Criteria, on Biopsy and Surgical Specimen: Preinvasive Lesions, from Epithelial Cell Hyperplasia to Carcinoma In Situ and Invasive Carcinoma – First-Line Immuno-Phenotyping of Prostate Diseases

  3. Molecular Pathology

    1. Front Matter

      Pages 43-43

    2. No Access

      Book Chapter

      Pages 45-56

      Molecular Determinants of Cancer-Related Inflammation

    3. No Access

      Book Chapter

      Pages 57-77

      Apoptosis and Autophagy

    4. No Access

      Book Chapter

      Pages 79-86

      Androgen Receptor and Steroidogenesis Pathway Control

    5. No Access

      Book Chapter

      Pages 87-109

      Neuroendocrine Differentiation in Prostate Cancer

    6. No Access

      Book Chapter

      Pages 111-125

      Metastatic Dissemination

    7. No Access

      Book Chapter

      Pages 127-142

      Resistance to Castration – Resistance to Drugs

    8. No Access

      Book Chapter

      Pages 143-157

      Crossroads of Signaling Pathways

  4. Genetic and Epigenetic Events in Prostate Cancer

    1. Front Matter

      Pages 159-159

    2. No Access

      Book Chapter

      Pages 161-182

      Gene Polymorphisms

    3. No Access

      Book Chapter

      Pages 183-193

      Expression Signature

    4. No Access

      Book Chapter

      Pages 195-200

      Mapping Prostate Cancer Aggressiveness Loci

    5. No Access

      Book Chapter

      Pages 201-210

      Epigenetic Mechanisms: Histone Acetylation, DNA Methylation, miRNA, Chromatin Modifiers

  5. A Modern Approach to Therapy of Prostate Cancer: Targeting the Deadly Subset

    1. Front Matter

      Pages 211-211

    2. No Access

      Book Chapter

      Pages 213-219

      Molecular Markers for Patient Selection and Stratification: Personalized Prognostic Predictive Models

    3. No Access

      Book Chapter

      Pages 221-231

      Targeting Tumor Angiogenesis

    4. No Access

      Book Chapter

      Pages 233-246

      Efficacy of Signal Transduction Inhibition in Advanced Prostate Cancer

    5. No Access

      Book Chapter

      Pages 247-254

      Therapeutic Targeting of the Bone Pre-metastatic Niche

    6. No Access

      Book Chapter

      Pages 255-269

      Counteracting Hypoxia in Radio-Resistant Metastatic Lesions

    7. No Access

      Book Chapter

      Pages 271-287

      “Synthetic Lethality”: Molecular Co-targeting to Restore the DNA Repair Mechanisms in Prostate Cancer Cells

  6. Back Matter

    Pages 289-296