2013

Spotlight on Familial and Hereditary Gastric Cancer

Editors:

ISBN: 978-94-007-6569-6 (Print) 978-94-007-6570-2 (Online)

Table of contents (17 chapters)

  1. Front Matter

    Pages i-xviii

  2. General Issues

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-10

      Historical Overview of Familial Gastric Cancer

    3. No Access

      Book Chapter

      Pages 11-18

      Frequency of Familial Gastric Cancer

    4. No Access

      Book Chapter

      Pages 19-23

      The Family Cancer Database

  3. Genetics and Epigenetics

    1. Front Matter

      Pages 25-25

    2. No Access

      Book Chapter

      Pages 27-33

      The E-Cadherin Gene, Structure and Function

    3. No Access

      Book Chapter

      Pages 35-49

      E-Cadherin Germline Mutations

    4. No Access

      Book Chapter

      Pages 51-76

      Molecular Mechanisms of Hereditary Diffuse Gastric Cancer Initiation and Progression

    5. No Access

      Book Chapter

      Pages 77-86

      Germline Missense Mutants in Hereditary Diffuse Gastric Cancer

    6. No Access

      Book Chapter

      Pages 87-96

      Alternative Mechanisms to Germline CDH1 Mutations in Hereditary Diffuse Gastric Cancer

    7. No Access

      Book Chapter

      Pages 97-110

      Beyond CDH1 Mutations: Causes of Hereditary Diffuse Gastric Cancer

    8. No Access

      Book Chapter

      Pages 111-125

      Non-CDH1-Associated Familial Gastric Cancer and Epigenetics Factors

  4. Pathology

    1. Front Matter

      Pages 127-127

    2. No Access

      Book Chapter

      Pages 129-139

      Hereditary Diffuse Gastric Cancer and Lobular Breast Carcinoma

    3. No Access

      Book Chapter

      Pages 141-156

      Pathology of Hereditary Gastric Cancer

  5. Management

    1. Front Matter

      Pages 157-157

    2. No Access

      Book Chapter

      Pages 159-165

      Clinical Criteria for Familial Gastric Cancer Definition

    3. No Access

      Book Chapter

      Pages 167-176

      Prophylactic Total Gastrectomy in CDH1 Germline Mutation Carriers

    4. No Access

      Book Chapter

      Pages 177-181

      Gastric Cancer in Other Inherited Syndromes

    5. No Access

      Book Chapter

      Pages 183-190

      Clinical Management of Familial Gastric Cancer

    6. No Access

      Book Chapter

      Pages 191-205

      Appendix

  6. Back Matter

    Pages 207-211