2013

The Tumor Immunoenvironment

Editors:

ISBN: 978-94-007-6216-9 (Print) 978-94-007-6217-6 (Online)

Table of contents (32 chapters)

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  1. Front Matter

    Pages i-xvi

  2. No Access

    Book Chapter

    Pages 1-12

    Role of the Immunological Environment in Cancer Initiation, Development and Progression

  3. Tumor Microenvironment and Immunoenvironment

    1. Front Matter

      Pages 13-13

    2. No Access

      Book Chapter

      Pages 15-38

      The Metastatic Microenvironment

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      Book Chapter

      Pages 39-82

      Tumor Infiltration by Immune Cells: Pathologic Evaluation and a Clinical Significance

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      Book Chapter

      Pages 83-104

      Immunologic Interpretation of Cancer Biology: Impact on Clinical Outcome

  4. Developmental Characteristics of the Tumor Immunoenvironment

    1. Front Matter

      Pages 105-105

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      Book Chapter

      Pages 107-133

      Development of Antitumor Cellular Immunity

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      Book Chapter

      Pages 135-175

      The Versatile World of Inflammatory Chemokines in Cancer

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      Book Chapter

      Pages 177-196

      Inflammation, Tumor Progression, and Immune Suppression

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      Book Chapter

      Pages 197-222

      Pleiotropic and Differential Functions of IL-1α and IL-1β Shape the Tumor Microenvironment and Affect the Outcome of Malignancies

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      Book Chapter

      Pages 223-250

      Impact of Obesity and Aging on the Tumor Immuno-Environment

  5. Tumor Escape from Immune Recognition

    1. Front Matter

      Pages 251-251

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      Book Chapter

      Pages 253-286

      MHC Class I Antigens and the Tumor Microenvironment

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      Book Chapter

      Pages 287-306

      Tumor-Produced Immune Regulating Factors

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      Book Chapter

      Pages 307-323

      Roles of Signaling Pathways in Cancer Cells and Immune Cells in Generation of Immunosuppressive Tumor-Associated Microenvironments

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      Book Chapter

      Pages 325-338

      T Cell Mulfunction in the Tumor Environment

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      Book Chapter

      Pages 339-360

      Signaling of Tumor-Induced Immunosuppression of Dendritic Cells

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      Book Chapter

      Pages 361-381

      Tumor Microenvironment may Shape the Function and Phenotype of NK Cells Through the Induction of Split Anergy and Generation of Regulatory NK Cells

  6. Immune Regulators in the Tumor Immunoenvironment

    1. Front Matter

      Pages 383-383

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      Book Chapter

      Pages 385-404

      The Role of Myeloid Derived Suppressor Cells in Cancer

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      Book Chapter

      Pages 405-430

      Macrophage Differentiation and Activation States in the Tumor Microenvironment

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      Book Chapter

      Pages 431-455

      Dendritic Cells and Cancer: Development, Dysfunction and Therapeutic Targets

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      Book Chapter

      Pages 457-478

      The Role of Tumor Associated Neutrophils in Cancer

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      Book Chapter

      Pages 479-509

      Mast Cell Modulation of the Tumor Microenvironment

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