Book 2012

MicroRNAs as Tools in Biopharmaceutical Production


ISBN: 978-94-007-5127-9 (Print) 978-94-007-5128-6 (Online)

Table of contents (8 chapters)

  1. Front Matter

    Pages 1-1

  2. Chapter

    Pages 1-13

    A General Introduction to MicroRNAs, Their Investigation and Exploitation in CHO Cell Lines

  3. Chapter

    Pages 15-27

    Biogenesis of Mammalian miRNA

  4. Chapter

    Pages 29-48

    Target Prediction Algorithms and Bioinformatics Resources for miRNA Studies

  5. Chapter

    Pages 49-64

    The CHO miRNA Transcriptome

  6. Chapter

    Pages 65-85

    MicroRNAs as Engineering Targets: Pathway Manipulation to Impact Bioprocess Phenotypes

  7. Chapter

    Pages 87-97

    MicroRNAs for Enhancement of CHO Cell Proliferation and Stability: Insights from Neuroblastoma Studies

  8. Chapter

    Pages 99-111

    MicroRNA Detection Methods for Mammalian Cell Lines and Their Applications in Therapeutic Protein Production

  9. Chapter

    Pages 113-121

    Manipulating Levels of Specific MicroRNAs in Mammalian Cells

  10. Back Matter

    Pages 119-119