Book Volume 63 2012

GPCR Signalling Complexes – Synthesis, Assembly, Trafficking and Specificity


ISBN: 978-94-007-4764-7 (Print) 978-94-007-4765-4 (Online)

Table of contents (14 chapters)

  1. Front Matter

    Pages i-viii

  2. Chapter

    Pages 1-21

    ER-Bound Steps in the Biosynthesis of G Protein-Coupled Receptors

  3. Chapter

    Pages 23-42

    Role of Chaperones in G Protein Coupled Receptor Signaling Complex Assembly

  4. Chapter

    Pages 43-65

    GPCR Oligomerization: Contribution to Receptor Biogenesis

  5. Chapter

    Pages 67-81

    The Functional Size of GPCRs – Monomers, Dimers or Tetramers?

  6. Chapter

    Pages 83-95

    Regulation of Post-Golgi Traffic of G Protein-Coupled Receptors

  7. Chapter

    Pages 97-111

    Regulated GPCR Trafficking to the Plasma Membrane: General Issues and the CCR5 Chemokine Receptor Example

  8. Chapter

    Pages 113-129

    Regulatory Processes Governing the Cell Surface Expression of LH and FSH Receptors

  9. Chapter

    Pages 131-153

    Chaperone-Mediated Assembly of G Protein Complexes

  10. Chapter

    Pages 155-180

    Synthesis and Assembly of G Protein βγ Dimers: Comparison of In Vitro and In Vivo Studies

  11. Chapter

    Pages 181-191

    Preferential Assembly of G-αβγ Complexes Directed by the γ Subunits

  12. Chapter

    Pages 193-223

    G Protein Trafficking

  13. Chapter

    Pages 225-240

    Differential Assembly of GPCR Signaling Complexes Determines Signaling Specificity

  14. Chapter

    Pages 241-262

    GPCR and Voltage-Gated Calcium Channels (VGCC) Signaling Complexes

  15. Chapter

    Pages 263-289

    Pharmacological Chaperones Correct Misfolded GPCRs and Rescue Function: Protein Trafficking as a Therapeutic Target

  16. Back Matter

    Pages 291-299