Book 2012

Innovation in Vaccinology

from design, through to delivery and testing


ISBN: 978-94-007-4542-1 (Print) 978-94-007-4543-8 (Online)

Table of contents (12 chapters)

  1. Front Matter

    Pages i-xii

  2. Vaccine design

    1. Front Matter

      Pages 1-1

    2. Chapter

      Pages 3-15

      Design of New Vaccines in the Genomic and Post-genomic Era

    3. Chapter

      Pages 17-42

      Comparing In Silico Results to In Vivo and Ex Vivo of Influenza-Specific Immune Responses After Vaccination or Infection in Humans

  3. Vaccine delivery

    1. Front Matter

      Pages 43-43

    2. Chapter

      Pages 45-63

      Virus Glycoproteins Tagged with the Human Fc Domain as Second Generation Vaccine Candidates

    3. Chapter

      Pages 65-86

      Engineered Viruses as Vaccine Platforms

    4. Chapter

      Pages 87-122

      Virus-Like Particles as Efficient Delivery Platform to Induce a Potent Immune Response

    5. Chapter

      Pages 123-134

      Filamentous Bacteriophages: An Antigen and Gene Delivery System

    6. Chapter

      Pages 135-178

      Liposomes and Other Nanoparticles as Cancer Vaccines and Immunotherapeutics

    7. Chapter

      Pages 179-203

      Plant-Based Vaccine Delivery Strategies

    8. Chapter

      Pages 205-228

      TLR Agonists as Vaccine Adjuvants

    9. Chapter

      Pages 229-248

      Mucosal Vaccines for Enteric Bacterial Pathogens

  4. Pre-clinical vaccine testing

    1. Front Matter

      Pages 249-249

    2. Chapter

      Pages 251-264

      The Importance of Animal Models in the Development of Vaccines

    3. Chapter

      Pages 265-285

      Correlates of Vaccine-Induced Immunity: Historical Perspectives and Future Challenges

  5. Back Matter

    Pages 287-288