Site-directed insertion of transgenes

Editors:

ISBN: 978-94-007-4530-8 (Print) 978-94-007-4531-5 (Online)

Table of contents (14 chapters)

  1. Front Matter

    Pages i-xiii

  2. Site-directed integration of transgenes

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-39

      Transgene Site-Specific Integration: Problems and Solutions

    3. No Access

      Book Chapter

      Pages 41-67

      Designing Non-viral Targeted Integrating Vectors for Genome Engineering in Vertebrates

  3. Integration based on homologous recombination

    1. Front Matter

      Pages 69-69

    2. No Access

      Book Chapter

      Pages 71-89

      Gene Targeting and Homologous Recombination in Saccharomyces cerevisiae

    3. No Access

      Book Chapter

      Pages 91-120

      Homologous Recombination in Mammals

    4. No Access

      Book Chapter

      Pages 121-145

      Engineered Zinc Finger Nucleases for Targeted Genome Editing

    5. No Access

      Book Chapter

      Pages 147-185

      Engineered Meganucleases for Genome Engineering Purposes

  4. Integration based on Site-specific recombination

    1. Front Matter

      Pages 187-187

    2. No Access

      Book Chapter

      Pages 189-209

      Cre/loxP, Flp/FRT Systems and Pluripotent Stem Cell Lines

    3. No Access

      Book Chapter

      Pages 211-239

      Site-Specific Recombination Using PhiC31 Integrase

    4. No Access

      Book Chapter

      Pages 241-265

      Modified Transposases for Site-Directed Insertion of Transgenes

    5. No Access

      Book Chapter

      Pages 267-284

      Targeted Plasmid Integration into the Human Genome by Engineered Recombinases

  5. Applications

    1. Front Matter

      Pages 285-285

    2. No Access

      Book Chapter

      Pages 287-315

      Gene Site-Specific Insertion in Plants

    3. No Access

      Book Chapter

      Pages 317-326

      Site-Directed Insertion of Transgenes in Drosophila

    4. No Access

      Book Chapter

      Pages 327-352

      Nuclease Mediated Targeted Genome Modification in Mammalian Cells

    5. No Access

      Book Chapter

      Pages 353-384

      Bio-applications Derived from Site-Directed Genome Modification Technologies

  6. Back Matter

    Pages 385-392