2012

Mortalin Biology: Life, Stress and Death

Editors:

ISBN: 978-94-007-3026-7 (Print) 978-94-007-3027-4 (Online)

Table of contents (21 chapters)

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  1. Front Matter

    Pages 1-1

  2. Structure and Function of Mortalin

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-20

      Birth of Mortalin: Multiple Names, Niches and Functions Connecting Stress, Senescence and Cancer

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      Book Chapter

      Pages 21-30

      Mortalin’s Machinery

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      Book Chapter

      Pages 31-54

      The Role of Mortalin in Iron Homeostasis

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      Book Chapter

      Pages 55-80

      Functional Characteristics of Mortalin

  3. Mortalin in Evolution2 Deocaris

    1. Front Matter

      Pages 81-81

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      Book Chapter

      Pages 83-95

      Mortalin and Drosophila DmHsp22: Two Mitochondrial Chaperones Regulating Aging and Carcinogenesis

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      Book Chapter

      Pages 97-113

      Mortalin in Invertebrates and The Induction of Apoptosis by Wild-Type p53 Following Defeat of Mortalin-Based Cytoplasmic Sequestration in Cancerous Clam Hemocytes

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      Book Chapter

      Pages 115-126

      Mortalin and Stem Cells: A Study from Planarians

  4. Mortalin in Health and Disease

    1. Front Matter

      Pages 127-127

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      Book Chapter

      Pages 129-137

      Mortalin in Cell Protection from Immune Attack

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      Book Chapter

      Pages 139-158

      Mortalin in Neurological Diseases

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      Book Chapter

      Pages 159-177

      Loss of Mortalin Function in Parkinson’s Disease-Supporting the Mitochondrial Pathway of Neurodegeneration

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      Book Chapter

      Pages 179-190

      Hsp75/mortalin and Protection from Ischemic Brain Injury

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      Book Chapter

      Pages 191-207

      Catecholamine Regulated Protein (CRP40), A Splice Variant of Mortalin-2: Functional Role in CNS Disorders

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      Book Chapter

      Pages 209-221

      Chaperonopathies: Diseases in Which Mortalin and Other Hsp-Chaperones Play a Role in Etiology and Pathogenesis

  5. Mortalin and Cancer

    1. Front Matter

      Pages 223-223

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      Book Chapter

      Pages 225-244

      Many Faces of Mortalin and Tid1

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      Book Chapter

      Pages 245-255

      Mortalin: A Positive Regulator of Centrosome Duplication and Amplification

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      Book Chapter

      Pages 257-265

      Mortalin Expression in Normal and Neoplastic Tissues

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      Book Chapter

      Pages 267-278

      Mortalin-p53 Interaction as a Target for Liver Cancer Therapy

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      Book Chapter

      Pages 279-291

      Mortalin Targeting Gadgets for Cancer Therapy

  6. Mortalin Based Technologies

    1. Front Matter

      Pages 293-293

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      Book Chapter

      Pages 295-305

      Cell Internalizing Anti-Mortalin Antibody for Generation of Illuminating MSCs for Long-Term In vitro and In vivo Tracking

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      Book Chapter

      Pages 307-322

      Mortalin Staining Pattern as a Reporter for Cell Based Anti-Cancer Drug Screening

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