Tumor-Associated Fibroblasts and their Matrix

Tumor Stroma

Editors:

ISBN: 978-94-007-0658-3 (Print) 978-94-007-0659-0 (Online)

Table of contents (22 chapters)

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  1. Front Matter

    Pages 1-1

  2. The Tumor Microenvironment

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-19

      Critical Roles of Stromal Fibroblasts in the Cancer Microenvironments

  3. Stromal Cell Diversity

    1. Front Matter

      Pages 21-21

    2. No Access

      Book Chapter

      Pages 23-36

      Functional Diversity of Fibroblasts

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      Book Chapter

      Pages 37-74

      The Role of the Myofibroblast in Fibrosis and Cancer Progression

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      Book Chapter

      Pages 75-89

      The Role of Myofibroblasts in Communicating Tumor Ecosystems

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      Book Chapter

      Pages 91-110

      Tumor Vessel Associated-Pericytes

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      Book Chapter

      Pages 111-123

      The Role of Cancer-Associated Adipocytes (CAA) in the Dynamic Interaction Between the Tumor and the Host

  4. The Tumor ECM

    1. Front Matter

      Pages 125-125

    2. No Access

      Book Chapter

      Pages 127-144

      Hyaluronan : A Key Microenvironmental Mediator of Tumor-Stromal Cell Interactions

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      Book Chapter

      Pages 145-158

      Function of Tenascins in the Tumor Stroma

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      Book Chapter

      Pages 159-174

      Fibulins and Their Role in the ECM

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      Book Chapter

      Pages 175-193

      Tumor Fibroblast-Associated Metalloproteases

  5. Tumor Modulating-Fibroblast Interactions

    1. Front Matter

      Pages 195-195

    2. No Access

      Book Chapter

      Pages 197-222

      Multiple Fibroblast Phenotypes in Cancer Patients: Heterogeneity in Expression of Migration Stimulating Factor

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      Book Chapter

      Pages 223-243

      TGF-β Signaling in Fibroblasts Regulates Tumor Initiation and Progression in Adjacent Epithelia

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      Book Chapter

      Pages 245-255

      The SDF-1 -Rich Tumour Microenvironment Provides a Niche for Carcinoma Cells

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      Book Chapter

      Pages 257-265

      Role of PDGF in Tumor-Stroma Interactions

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      Book Chapter

      Pages 267-282

      Radiation-Induced Microenvironments and Their Role in Carcinogenesis

  6. Tumor-Modulating ECM Interactions

    1. Front Matter

      Pages 283-283

    2. No Access

      Book Chapter

      Pages 285-300

      The Extracellular Matrix as a Multivalent Signaling Scaffold that Orchestrates Tissue Organization and Function

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      Book Chapter

      Pages 301-346

      SPARC and the Tumor Microenvironment

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      Book Chapter

      Pages 347-360

      Integrin-Extracellular Matrix Interactions

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      Book Chapter

      Pages 361-380

      The Multifaceted Role of Cancer Associated Fibroblasts in Tumor Progression

  7. Therapeutic Application/Targeting

    1. Front Matter

      Pages 381-381

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      Book Chapter

      Pages 383-401

      Cancer Associated Fibroblasts as Therapeutic Targets

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