Circulating Nucleic Acids in Plasma and Serum

Proceedings of the 6th international conference on circulating nucleic acids in plasma and serum held on 9-11 November 2009 in Hong Kong.

  • Peter B. Gahan
Conference proceedings

DOI: 10.1007/978-90-481-9382-0

Table of contents (37 papers)

  1. Front Matter
    Pages i-xx
  2. Current Developments

    1. Front Matter
      Pages 1-1
  3. Nucleic Acids in Oncology - Diagnosis and Prognosis and Metastases

    1. Front Matter
      Pages 13-13
    2. Circulating Tumor-Related DNA Alterations as Prostate Cancer Biomarkers
      Laurent Lessard, Eiji Sumami, Dave S.B. Hoon
      Pages 21-27
    3. Parallel Tagged 454 Sequencing for the Characterization of Circulating DNA
      Maniesh van der Vaart, Dmitry V. Semenov, Elena V. Kuligina, Vladimir A. Richter, Piet J. Pretorius
      Pages 29-33
    4. Advanced Analysis of Human Plasma Circulating DNA Sequences Produced by Parallel Tagged Sequencing on the 454 Platform
      Maniesh van der Vaart, Dmitry V. Semenov, Elena V. Kuligina, Vladimir A. Richter, Piet J. Pretorius
      Pages 35-40
    5. Concentration and Distribution of Single-Copy β-Actin Gene and LINE-1 Repetitive Elements in Blood of Lung Cancer Patients
      Anastasia A. Ponomaryova, Elena Y. Rykova, Nadezhda V. Cherdyntseva, Tatiana E. Skvortsova, Anna V. Cherepanova, Evgeniy S. Morozkin et al.
      Pages 41-45
    6. Plasma DNA Methylation Analysis in Predicting Short-Term Recurrence of Surgical Patients with Non-small Cell Lung Cancer (NSCLC)
      Qingqing Ding, Yuan Mu, Shiyang Pan, Yongqian Shu, Shijiang Zhang, Bingfeng Zhang et al.
      Pages 47-55
    7. Blood Based Methylated DNA and Tumor-Specific Protein Analysis in Gastric Cancer Diagnostics
      Elena V. Elistratova, Petr I. Shelestyuk, Valentina I. Permyakova, Elena D. Chikova, Sergey A. Tuzikov, Valentin V. Vlassov et al.
      Pages 57-61
    8. Increase in Circulating MicroRNA Levels in Blood of Ovarian Cancer Patients
      Carina Roth, Sabine Kasimir-Bauer, Martin Heubner, Klaus Pantel, Heidi Schwarzenbach
      Pages 63-71
    9. The Course of Circulating Nucleosomes in Liver Cancer Patients Undergoing Transarterial Chemoembolization Therapy
      Nikolaus Kohles, Dorothea Nagel, Dietrich Jüngst, Jürgen Durner, Petra Stieber, Stefan Holdenrieder
      Pages 73-77
    10. Presence of Nucleosomes in Cerebrospinal Fluid of Glioblastoma Patients – Potential for Therapy Monitoring
      Stefan Holdenrieder, Andreas Spuler, Michael Tischinger, Dorothea Nagel, Petra Stieber
      Pages 79-84
    11. Circulating Nucleosomes and DNAse in Breast Cancer Patients During Neoadjuvant Chemotherapy
      Oliver J. Stoetzer, Debora M.I. Fersching, Stefan Holdenrieder
      Pages 85-89
    12. Circulating Nucleosomes in Cancer Patients with Liver Metastases Undergoing Selective Internal Radiation Therapy Using Yttrium-90 Labelled Microspheres
      Yvonne Fehr, Stefan Holdenrieder, Ralf-Thorsten Hoffmann, Klaus Tatsch, Tobias Jakobs, Dorothea Nagel et al.
      Pages 91-95
    13. H3K9me3/H4K20me3 Ratio in Circulating Nucleosomes as Potential Biomarker for Colorectal Cancer
      Ugur Deligezer, Elif Z. Akisik, Ebru E. Akisik, Müge Kovancilar, Dursun Bugra, Nilgün Erten et al.
      Pages 97-103
    14. Functionality of CNAPS in Cancer: The Theory of Genometastasis
      Dolores C. García-Olmo, Hector Guadalajara, Carolina Dominguez-Berzosa, María G. Picazo, Mariano García-Arranz, Damián García-Olmo
      Pages 105-108
  4. Nucleic Acids in Foetal Medicine

    1. Front Matter
      Pages 109-109
    2. Circulating Fetal DNA/RNA in Maternal Plasma for Aneuploidy Detection
      Y. K. Tong, R.W.K. Chiu, Y.M.D. Lo
      Pages 111-124

About these proceedings


DNA and RNA fractions have been isolated from a variety of sources including: whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and patients. The ability to isolate, quantify, and analyze these molecules has led to the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis. This volume encompasses the proceedings of the 6th international conference on circulating nucleic acids in plasma and serum held from the 9th to the 11th of November 2009 in Hong Kong. The topics that are covered in these proceedings include: - Nucleic Acids in Oncology - Nucleic Acids in Foetal Medicine - The Biology of CNAPS - New Technologies for CNAPS - Other Clinical Exploitation of CNAPS


Circulating nucleic acids Early diagnostic markers Foetal disorders Oncology Roles in prognosis

Editors and affiliations

  • Peter B. Gahan
    • 1
  1. 1., Anatomy & Human SciencesKing's College LondonLondonUnited Kingdom

Bibliographic information

  • Copyright Information Springer Science+Business Media B.V. 2011
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-90-481-9381-3
  • Online ISBN 978-90-481-9382-0