2010

A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics

Editors:

ISBN: 978-90-481-3143-3 (Print) 978-90-481-3144-0 (Online)

Table of contents (16 chapters)

  1. Front Matter

    Pages i-xv

  2. Introduction

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-26

      From Hypertension (+) to Asthma: Interactions with the Adenosine A3 Receptor from a Personal Perspective

  3. Physico-chemical Properties and Molecular Biology

    1. Front Matter

      Pages 28-28

    2. No Access

      Book Chapter

      Pages 29-48

      Thermodynamic Analysis in Drug–Receptor Binding: The A3 Adenosine Receptor

    3. No Access

      Book Chapter

      Pages 49-58

      Pharmacology and Molecular Biology of A3 Adenosine Receptors

  4. Signal Transduction

    1. Front Matter

      Pages 60-60

    2. No Access

      Book Chapter

      Pages 61-73

      Regulation of Second Messenger Systems and Intracellular Pathways

    3. No Access

      Book Chapter

      Pages 75-90

      The Desensitisation as A3 Adenosine Receptor Regulation: Physiopathological Implications

  5. Medicinal Chemistry

    1. Front Matter

      Pages 92-92

    2. No Access

      Book Chapter

      Pages 93-120

      A3 Adenosine Receptor Agonists: History and Future Perspectives

    3. No Access

      Book Chapter

      Pages 121-147

      A3 Adenosine Receptor Antagonists: History and Future Perspectives

    4. No Access

      Book Chapter

      Pages 149-161

      Molecular Modeling and Reengineering of A3 Adenosine Receptors

  6. Effects on Tissues and Organs and Therapeutic Applications

    1. Front Matter

      Pages 164-164

    2. No Access

      Book Chapter

      Pages 165-188

      Adenosine A3 Receptor Signaling in the Central Nervous System

    3. No Access

      Book Chapter

      Pages 189-208

      Cardiovascular Biology of the A3 Adenosine Receptor

    4. No Access

      Book Chapter

      Pages 209-233

      A3 Adenosine Receptor in the Pulmonary System

    5. No Access

      Book Chapter

      Pages 235-256

      A3 Adenosine Receptor Regulation of Cells of the Immune System and Modulation of Inflammation

    6. No Access

      Book Chapter

      Pages 257-280

      Adenosine A3 Receptors in Muscle Protection

    7. No Access

      Book Chapter

      Pages 281-288

      A3 Adenosine Receptors, HIF-1 Modulation and Atherosclerosis

  7. Inflammatory and Auto-Immune Diseases

    1. Front Matter

      Pages 290-290

    2. No Access

      Book Chapter

      Pages 291-298

      Rheumatoid Arthritis: History, Molecular Mechanisms and Therapeutic Applications

  8. Cancer

    1. Front Matter

      Pages 300-300

    2. No Access

      Book Chapter

      Pages 301-317

      Agonists and Antagonists: Molecular Mechanisms and Therapeutic Applications

  9. Back Matter

    Pages 319-322