Neurodegeneration in Multiple Sclerosis

Editors:

ISBN: 978-88-470-0390-3 (Print) 978-88-470-0391-0 (Online)

Table of contents (17 chapters)

  1. Front Matter

    Pages I-XI

  2. Background

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-9

      Neuropathological Advances in Multiple Sclerosis

    3. No Access

      Book Chapter

      Pages 11-20

      Neurophysiology

  3. MRI Techniques to Assess Neurodegeneration

    1. Front Matter

      Pages 21-21

    2. No Access

      Book Chapter

      Pages 23-35

      Atrophy

    3. No Access

      Book Chapter

      Pages 37-45

      T1 Black Holes and Gray Matter Damage

    4. No Access

      Book Chapter

      Pages 47-53

      Magnetization Transfer Imaging

    5. No Access

      Book Chapter

      Pages 55-64

      Perfusion MR I

    6. No Access

      Book Chapter

      Pages 65-74

      Diffusion-Weighted Imaging

    7. No Access

      Book Chapter

      Pages 75-83

      Proton MR Spectroscopy

    8. No Access

      Book Chapter

      Pages 85-104

      Functional MRI

  4. Evaluation of MRI Outcomes

    1. Front Matter

      Pages 105-105

    2. No Access

      Book Chapter

      Pages 107-112

      Validation of MRI Surrogates

    3. No Access

      Book Chapter

      Pages 113-125

      Defining Responders and Non-responders

    4. No Access

      Book Chapter

      Pages 127-149

      Predictive Models in Multimodal Imaging

  5. Lessons from Other Neurodegenerative Diseases

    1. Front Matter

      Pages 151-151

    2. No Access

      Book Chapter

      Pages 153-161

      Alzheimer’s Disease

    3. No Access

      Book Chapter

      Pages 163-181

      Other Neurodegenerative Conditions

    4. No Access

      Book Chapter

      Pages 183-207

      Incorporation of Other Biomarkers

  6. Designing MS Trials for Neurodegeneration

    1. Front Matter

      Pages 209-209

    2. No Access

      Book Chapter

      Pages 211-220

      Critical Review of Existing Trials

    3. No Access

      Book Chapter

      Pages 221-232

      Design for the Next Trials of Neurodegeneration

  7. Back Matter

    Pages 233-236