New Frontiers in Lifestyle-Related Diseases

  • Akira Miyazaki
  • Michio Imawari
Conference proceedings

DOI: 10.1007/978-4-431-76428-1

Table of contents (19 papers)

  1. Front Matter
    Pages I-XXII
  2. Regulation of Feeding and Energy Homeostasis in the Brain

    1. Front Matter
      Pages 1-1
    2. Orphan Neuropeptides and the Regulation of Food Intake
      Hiroshi Nagasaki, Yanling Xu, Yumiko Saito, Olivier Civelli
      Pages 3-19
    3. Neuronal Mechanisms of Feeding Regulation by Peptides
      Masamitsu Nakazato, Hiroaki Ueno
      Pages 21-28
    4. Distribution and Localization of Galanin-like peptide (GALP) in Brain
      Fumiko Takenoya, Haruaki Kageyama, Seiji Shioda
      Pages 29-38
    5. Functional Analysis of GALP in Feeding Regulation
      Haruaki Kageyama, Koji Toshinai, Yukari Date, Masamitsu Nakazato, Fumiko Takenoya, Seiji Shioda
      Pages 39-45
    6. Regulation of Energy Homeostasis by GALP
      Seiji Shioda, Haruaki Kageyama, Fumiko Takenoya, Yukari Date, Masamitsu Nakazato, Toshimasa Osaka et al.
      Pages 47-53
  3. Lipid Metabolism and Atherosclerosis

    1. Front Matter
      Pages 55-55
    2. Regulation of Intracellular Lipid Storage and Adipose Differentiation-Related Protein (ADRP)
      Hiroyuki Itabe, Yutaka Masuda, Naoko Sasabe, Keiko Kitazato, Hiroyuki Arai, Tatsuya Takano
      Pages 81-88
  4. Risk Factors for Cardiovascular Diseases

    1. Front Matter
      Pages 97-97
    2. Sleep Apnea and Metabolic and Cardiovascular Complications
      Christopher P. O’Donnell
      Pages 99-105
    3. Sleep Apnea Syndrome and Atherosclerosis
      Kenji Minoguchi
      Pages 107-114
    4. Significance of Small Dense Low-Density Lipoproteins in Coronary Heart Disease
      Shinji Koba, Tsutomu Hirano, Yuuya Yokota, Fumiyoshi Tsunoda, Yoshihisa Ban, Takayuki Sato et al.
      Pages 115-123
    5. Statin decreases IL-1 and LPS-induced inflammatory cytokines production in oral epithelial cells
      Michihiko Usui, Reiko Suda, Yasushi Miyazawa, Makoto Kobayashi, Yoshimasa Okamatsu, Hisashi Takiguchi et al.
      Pages 125-131
  5. Poster Sessions

    1. Front Matter
      Pages 133-133
    2. Onco-suppressor p53 protein prevents an Alzheimer disease mouse model, Pin1-null mouse from the increase of presenilin-1
      Katsuhiko Takahashi, Kiyoe Shimazaki, Takashi Obama, Rina Kato, Hiroyuki Itabe, Hirotada Akiyama et al.
      Pages 135-138

About these proceedings


It is my great pleasure to publish New Frontiers in Lifestyle-Related Dis­ eases, the proceedings of the Showa University International Symposium for Life Sciences, 3rd Annual Meeting, held at Showa University on Sep­ tember 13, 2006. This symposium was supported, in part, by Grants for the Promotion of the Advancement of Education and Research in Graduate Schools and Ordinary Expenses for Private Schools from the Ministry of Education, Culture, Sports, Science, and Technology of Japan. On behalf of Showa University, I would like to express my deepest thanks to all the authors and editors for their great contribution to the publication of this memorable book that accelerates research activity in lifestyle-related diseases. Akiyoshi Hosoyamada, M.D., Ph.D. President, Showa University Tokyo, Japan September 2007 v Preface The leading cause of death in Western countries and some developing countries is atherosclerotic cardiovascular diseases. Among them, acute myocardial infarction is the most common type of fatal disease, caused by the progression of atherosclerosis characterized by accumulation of choles­ terol in vascular walls. Development of atherosclerosis is greatly enhanced by major risk factors for cardiovascular diseases such as obesity, hyperlip­ idemia, diabetes (hyperglycemia), and hypertension. Among those, obesity frequently initiates a metabolic change that subsequently induces hyperlip­ idemia, diabetes, hypertension, and eventually atherosclerotic cardiovascu­ lar diseases. Because obesity and its related disorders largely depend on lifestyle factors such as high calorie intake and low physical activity, a series of disorders are termed lifestyle-related diseases.


Atherosclerosis Coronary Heart Disease Diabetes Lifestyle-Related Diseases Lipid Metabolism Risk Factor homeostasis

Editors and affiliations

  • Akira Miyazaki
    • 1
  • Michio Imawari
    • 2
  1. 1.Department of BiochemistryShowa University School of MedicineTokyoJapan
  2. 2.Second Department of Internal MedicineShowa University School of MedicineTokyoJapan

Bibliographic information

  • Copyright Information Springer Japan 2008
  • Publisher Name Springer, Tokyo
  • eBook Packages Medicine
  • Print ISBN 978-4-431-76427-4
  • Online ISBN 978-4-431-76428-1