Ischemic Blood Flow in the Brain

  • Yasuo Fukuuchi
  • Minoru Tomita
  • Atsuo Koto
Conference proceedings

DOI: 10.1007/978-4-431-67899-1

Part of the Keio University Symposia for Life Science and Medicine book series (KEIO, volume 6)

Table of contents (55 papers)

  1. Front Matter
    Pages I-XX
  2. Honorary Lecture

  3. Endothelium, Mechanosensors, Glycocalyx

  4. Endothelium, BBB Disruption

    1. Front Matter
      Pages 47-47
    2. Proteolytic Opening of the Blood-Brain Barrier During Neuroinflammation
      Gary A. Rosenberg, Diedre Hofinger, Edward Y. Estrada, James A. Wallace
      Pages 57-63
    3. Endothelial Dysfunction After Brain Ischemia and Reperfusion
      Timur D. Vlasov, Victor I. Amosov, Dmitry E. Korzhevski
      Pages 64-69
    4. Temporal Profile of Ischemic Edema:Comparison of Ultrastructure,Gravimetry, and Evans Blue Permeability
      U. Ito, T. Kuroiwa, S. Hanyu, Y. Hakamata, S. Ito, I. Nakano et al.
      Pages 76-82
  5. Ischemia and Gene Expression

    1. Front Matter
      Pages 89-89
    2. Effects of lschemia on Expression of Cyclooxygenase and Endothelial Nitric Oxide Synthase in the Cerebral Circulation
      David W. Busija, Ferenc Domoki, Nishadi Thrikawala, Ferenc Bari
      Pages 91-97
    3. Role of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 in the Mechanisms of Ischemic Brain Injury
      Costantino Iadecola, Shigeru Nogawa, Masao Nagayama, Tomiko Nagayama, Kiyoshi Niwa, Xueren Zhao et al.
      Pages 98-107

About these proceedings

Introduction

Because stroke is essentially a disease of the vessels and blood flow, the most fundamental aspects of ischemic blood flow in the brain are under investigation by researchers. Their work was the focus of the sixth in the series of Keio University International Symposia for Life Sciences and Medicine, held in Tokyo in 1999. Selected here are 55 papers from the symposium, covering the buffy coat (glycocalyx) of endothelial cells, the blood-brain barrier and permeability, gene expression, vascular reactivity, dysregulation, inflammatory deterioration, cortical spreading depression, edema, microvascular derangement, and pathology, in ten major sections. The book includes the thought-provoking discussions that followed the presentations, thus providing an invaluable source of up-to-date information not only for researchers investigating microcirculation but also for clinicians implementing the most effective treatment for stroke patients.

Keywords

Glycocalyx Inflammatory process in ischemia Ischemic derangement of cerebral blood flow brain circulation depression disturbed vascular reactivity oxidative stress spreading depression stroke

Editors and affiliations

  • Yasuo Fukuuchi
    • 1
  • Minoru Tomita
    • 1
  • Atsuo Koto
    • 1
  1. 1.Department of Neurology School of MedicineKeio UniversityTokyoJapan

Bibliographic information

  • Copyright Information Springer-Verlag Tokyo 2001
  • Publisher Name Springer, Tokyo
  • eBook Packages Springer Book Archive
  • Print ISBN 978-4-431-67990-5
  • Online ISBN 978-4-431-67899-1