New Frontiers in Regenerative Medicine

  • Mitsuo Kusano
  • Seiji Shioda
Conference proceedings

DOI: 10.1007/978-4-431-38208-9

Table of contents (17 papers)

  1. Front Matter
    Pages I-XX
  2. Digestive and Integumentary System

    1. Front Matter
      Pages 1-1
    2. Hepatocyte transplantation for liver disease
      Keitaro Mitamura, Ewa Ellis, Toshio Miki, Stephen Strom
      Pages 3-7
    3. Novel Model for Evaluation of Human Skin Injury
      Bunsho Kao, Yoshiyasu Amikura, Eri Honda, Yosuke Tomizuka, Yoshiaki Hosaka
      Pages 33-36
    4. Heparin enhances BMP activity by maintaining high levels of nuclear phosphorylated Smad1/5/8
      Baohong Zhao, Takenobu Katagiri, Hiromitsu Toyoda, Takatora Takada, Tatsuya Koike, Kunio Takaoka et al.
      Pages 37-42
  3. The Cardiovascular System

    1. Front Matter
      Pages 43-43
    2. Importance of Neutrophil and Erythroblast for the efficacy of Bone-marrow Cell Implantation in Peripheral Artery Disease
      Hiroshi Suzuki, Yoshitaka Iso, Taro Kusuyama, Yasutoshi Omori, Teruko Soda, Takatoshi Sato et al.
      Pages 57-65
    3. Bone marrow derived cells contribute to arterial remodeling
      Makoto Shoji, Hiroshi Suzuki, Taro Kusuyama, Yasutoshi Omori, Teruko Soda, Fumiyoshi Tsunoda et al.
      Pages 67-74
    4. TNF-α mobilizes bone marrow derived cells to vascular wall, resulting in neointima formation through its inflammatory effects
      Makoto Shoji, Hiroshi Suzuki, Taro Kusuyama, Yasutoshi Omori, Teruko Soda, Fumiyoshi Tsunoda et al.
      Pages 75-82
    5. Angiogenesis induced by adhesion between polymorphonuclear leukocyte and endothelial cell via intercellular adhesion molecule-1
      Masako Yasuda, Masayuki Ohbayashi, Shunichi Shimizu, Toshinori Yamamoto
      Pages 83-93
    6. Improvement of severe ulcer of buerger’s disease by bone-marrow mononuclear cell transplantation: a case report
      Teruko Soda, Hiroshi Suzuki, Taro Kusuyama, Yuya Yokota, Yasutoshi Omori, Takatoshi Sato et al.
      Pages 95-100
    7. Cardioprotective effect of G-CSF administration after coronary reperfusion in swine AMI model
      Takatoshi Sato, Hiroshi Suzuki, Taro Kusuyama, Yasutoshi Omori, Teruko Soda, Fumiyoshi Tsunoda et al.
      Pages 101-109
  4. The Nervous System

    1. Front Matter
      Pages 111-111
    2. Adult neurogenesis in the hippocampus
      Tatsunori Seki
      Pages 113-120
    3. Involvement of β Isoform of PKC in PACAP-induced Differentiation of Neural Stem Cells into Astrocytes
      Shigeo Nakajo, Jun Watanabe, Motoi Ohba, Fusako Ohno, Sakae Kikuyama, Kazuyasu Nakaya et al.
      Pages 121-134
    4. Does PACAP have therapeutic potential in the field of neuroregenerative medicine?
      Hirokazu Ohtaki, Tomoya Nakamachi, Jun Watanabe, Sachiko Yofu, Masaji Matsunaga, Ryosuke Matsuno et al.
      Pages 135-142

About these proceedings


Rapid advances in stem cell biology have raised exciting possibilities of replacing damaged or lost tissues and cells by activation of in vitro-expanded stem cells or their progeny. This book examines many of the unresolved problems as well as future applications of regenerative medicine. Areas of focus include the nervous system and hippocampal neurogenesis, along with the functional significance of pro-inflammatory cytokines, and the production of free radicals after brain ischemia; the digestive and integumentary systems, dealing with hepatocyte transplantation, pancreatic regeneration, and skin and hair regeneration; and the cardiovascular system, with repair and remodeling of the lung and heart, and arterial remodeling with bone marrow-derived progenitor cells. In addition to animal experiments, results of research on human tissues and organs are included. Researchers in the field will find this volume an invaluable source of reference in their work.


Integument Nervous System biology brain cardiovascular cardiovascular system cell cell biology heart implantation medicine system therapy tissue transplantation

Editors and affiliations

  • Mitsuo Kusano
    • 1
  • Seiji Shioda
    • 1
  1. 1.Showa University School of MedicineTokyoJapan

Bibliographic information

  • Copyright Information Springer 2007
  • Publisher Name Springer, Tokyo
  • eBook Packages Medicine
  • Print ISBN 978-4-431-38207-2
  • Online ISBN 978-4-431-38208-9