Sphingolipids: Basic Science and Drug Development

Editors:

ISBN: 978-3-7091-1367-7 (Print) 978-3-7091-1368-4 (Online)

Table of contents (13 chapters)

  1. Front Matter

    Pages i-viii

  2. Basic Mechanisms

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-32

      The Genetics of Sphingolipid Hydrolases and Sphingolipid Storage Diseases

    3. No Access

      Book Chapter

      Pages 33-55

      Sphingolipids and Membrane Domains: Recent Advances

    4. No Access

      Book Chapter

      Pages 57-76

      Sphingolipid Metabolism and Neutral Sphingomyelinases

    5. No Access

      Book Chapter

      Pages 77-88

      Acid Sphingomyelinase

    6. No Access

      Book Chapter

      Pages 89-107

      Ceramide Synthases: Reexamining Longevity

    7. No Access

      Book Chapter

      Pages 109-126

      Membrane Channels Formed by Ceramide

    8. No Access

      Book Chapter

      Pages 127-152

      Genetic Disorders of Simple Sphingolipid Metabolism

    9. No Access

      Book Chapter

      Pages 153-166

      The Role of Ceramide-1-Phosphate in Biological Functions

  3. Drug Development

    1. Front Matter

      Pages 167-167

    2. No Access

      Book Chapter

      Pages 169-186

      Functional Inhibitors of Acid Sphingomyelinase (FIASMAs)

    3. No Access

      Book Chapter

      Pages 187-196

      Novel Drugs Targeting Sphingolipid Metabolism

    4. No Access

      Book Chapter

      Pages 197-210

      The Therapeutic Potential of Nanoscale Sphingolipid Technologies

    5. No Access

      Book Chapter

      Pages 211-238

      Novel Chemotherapeutic Drugs in Sphingolipid Cancer Research

    6. No Access

      Book Chapter

      Pages 239-253

      Pharmacology of the Sphingosine-1-Phosphate Signalling System

  4. Back Matter

    Pages 255-259