1970

Evolution by Gene Duplication

Authors:

ISBN: 978-3-642-86661-6 (Print) 978-3-642-86659-3 (Online)

Table of contents (22 chapters)

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  1. Front Matter

    Pages I-XV

  2. Introduction

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      Pages 1-2

      Introduction

  3. The Creation of Life Based on the Inherent Complementality between Purine and Pyrimidine Bases

    1. Front Matter

      Pages 3-3

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      Pages 3-4

      Perpetuation of the Germ Line

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      Pages 4-15

      Replication of Nucleic Acids on the Basis of A-T, G-C Complementality and the Origin of Life

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      Pages 15-20

      Chromosomes of Eukaryotes

  4. Mutation and the Conservative Nature of Natural Selection

    1. Front Matter

      Pages 21-21

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      Pages 21-26

      Mutation as a Change in the Base Sequence of a DNA Cistron

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      Pages 26-32

      Forbidden Mutations

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      Pages 32-40

      Tolerable Mutations

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      Pages 41-47

      The Conservative Nature of Chromosomal Evolution

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      Pages 48-55

      The Spontaneous Mutation Rate

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      Pages 55-58

      The Rate of Evolution and the Importance of Isolation

  5. Why Gene Duplication?

    1. Front Matter

      Pages 59-59

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      Pages 59-65

      Duplication for the Sake of Producing More of the Same

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      Pages 65-67

      The Attainment of a Permanent Heterozygous Advantage by the Incorporation of Two Former Alleles into the Genome

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      Pages 67-71

      The Differential Regulation of Former Alleles and Their Transformation to Isozyme Genes

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      Pages 71-82

      The Creation of a New Gene from a Redundant Duplicate of an Old Gene

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      Pages 82-88

      Duplication of Regulatory Genes and Receptors

  6. Mechanisms of Gene Duplication

    1. Front Matter

      Pages 89-89

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      Pages 89-97

      Tandem Duplication Involving Part of One Linkage Group at a Time

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      Pages 98-106

      Polyploidy: Duplication of the Entire Genome

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      Pages 107-110

      Other Mechanisms for Achieving Gene Duplication

  7. Evolution of Vertebrate Genomes

    1. Front Matter

      Pages 111-111

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      Pages 111-123

      Primitives Inherit the Earth

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      Pages 124-132

      Nature’s Great Experiment with Gene Duplication during Evolution from Tunicate-like Creatures to Fish

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