Challenges and Opportunities for Respiratory Syncytial Virus Vaccines

Editors:

ISBN: 978-3-642-38918-4 (Print) 978-3-642-38919-1 (Online)

Table of contents (20 chapters)

  1. Front Matter

    Pages i-xi

  2. Virology, Pathogenesis, and Clinical and Epidemiological Features of Disease

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-38

      Respiratory Syncytial Virus: Virology, Reverse Genetics, and Pathogenesis of Disease

    3. No Access

      Book Chapter

      Pages 39-57

      Clinical and Epidemiologic Features of Respiratory Syncytial Virus

    4. No Access

      Book Chapter

      Pages 59-82

      Influence of Respiratory Syncytial Virus Strain Differences on Pathogenesis and Immunity

    5. No Access

      Book Chapter

      Pages 83-104

      Structure and Function of Respiratory Syncytial Virus Surface Glycoproteins

    6. No Access

      Book Chapter

      Pages 105-118

      Respiratory Syncytial Virus and Reactive Airway Disease

  3. Host Response to Infection and Genetics of Disease

    1. Front Matter

      Pages 119-119

    2. No Access

      Book Chapter

      Pages 121-137

      Human Genetics and Respiratory Syncytial Virus Disease: Current Findings and Future Approaches

    3. No Access

      Book Chapter

      Pages 139-154

      Innate Immune Responses to Respiratory Syncytial Virus Infection

    4. No Access

      Book Chapter

      Pages 155-171

      The Adaptive Immune Response to Respiratory Syncytial Virus

    5. No Access

      Book Chapter

      Pages 173-191

      Respiratory Syncytial Virus Mechanisms to Interfere with Type 1 Interferons

    6. No Access

      Book Chapter

      Pages 193-209

      Host Gene Expression and Respiratory Syncytial Virus Infection

    7. No Access

      Book Chapter

      Pages 211-231

      Consequences of Immature and Senescent Immune Responses for Infection with Respiratory Syncytial Virus

  4. Vaccine Platforms and Treatment Options

    1. Front Matter

      Pages 233-233

    2. No Access

      Book Chapter

      Pages 235-258

      Respiratory Syncytial Virus Disease: Prevention and Treatment

    3. No Access

      Book Chapter

      Pages 259-284

      Live-Attenuated Respiratory Syncytial Virus Vaccines

    4. No Access

      Book Chapter

      Pages 285-306

      Subunit and Virus-Like Particle Vaccine Approaches for Respiratory Syncytial Virus

    5. No Access

      Book Chapter

      Pages 307-324

      Gene-Based Vaccine Approaches for Respiratory Syncytial Virus

  5. Animal and Tissue Culture Models of Infection

    1. Front Matter

      Pages 325-325

    2. No Access

      Book Chapter

      Pages 327-345

      Bovine Model of Respiratory Syncytial Virus Infection

    3. No Access

      Book Chapter

      Pages 347-358

      The Cotton Rat Sigmodon Hispidus Model of Respiratory Syncytial Virus Infection

    4. No Access

      Book Chapter

      Pages 359-369

      The Mouse Model of Respiratory Syncytial Virus Disease

    5. No Access

      Book Chapter

      Pages 371-387

      Human Airway Epithelial Cell Cultures for Modeling Respiratory Syncytial Virus Infection

  6. Conclusions

    1. Front Matter

      Pages 389-389

    2. No Access

      Book Chapter

      Pages 391-404

      Challenges and Opportunities for Respiratory Syncytial Virus Vaccines

  7. Back Matter

    Pages 405-409