Book Volume 16 2014

Systems Biology of Metabolic and Signaling Networks

Energy, Mass and Information Transfer

Editors:

ISBN: 978-3-642-38504-9 (Print) 978-3-642-38505-6 (Online)

Table of contents (13 chapters)

  1. Front Matter

    Pages i-x

  2. Introduction

    1. Front Matter

      Pages 1-1

    2. No Access

      Chapter

      Pages 3-17

      From Physiology, Genomes, Systems, and Self-Organization to Systems Biology: The Historical Roots of a Twenty-First Century Approach to Complexity

    3. No Access

      Chapter

      Pages 19-35

      Complex Systems Biology of Networks: The Riddle and the Challenge

  3. Systems Biology of Signaling Networks

    1. Front Matter

      Pages 37-37

    2. No Access

      Chapter

      Pages 39-62

      The Control Analysis of Signal Transduction

    3. No Access

      Chapter

      Pages 63-114

      MicroRNAs and Robustness in Biological Regulatory Networks. A Generic Approach with Applications at Different Levels: Physiologic, Metabolic, and Genetic

    4. No Access

      Chapter

      Pages 115-144

      Dynamics of Mitochondrial Redox and Energy Networks: Insights from an Experimental–Computational Synergy

    5. No Access

      Chapter

      Pages 145-162

      Adenylate Kinase Isoform Network: A Major Hub in Cell Energetics and Metabolic Signaling

  4. Systems Biology of Cellular Structures and Fluxes

    1. Front Matter

      Pages 163-163

    2. No Access

      Chapter

      Pages 165-178

      Moonlighting Function of the Tubulin Cytoskeleton: Macromolecular Architectures in the Cytoplasm

    3. No Access

      Chapter

      Pages 179-211

      Metabolic Dissipative Structures

    4. No Access

      Chapter

      Pages 213-239

      Systems Biology Approaches to Cancer Energy Metabolism

  5. Systems Biology of Organ Function

    1. Front Matter

      Pages 241-241

    2. No Access

      Chapter

      Pages 243-260

      Network Dynamics in Cardiac Electrophysiology

    3. No Access

      Chapter

      Pages 261-320

      Systems Level Regulation of Cardiac Energy Fluxes Via Metabolic Cycles: Role of Creatine, Phosphotransfer Pathways, and AMPK Signaling

  6. Systems Biology of Microorganisms

    1. Front Matter

      Pages 321-321

    2. No Access

      Chapter

      Pages 323-349

      Temporal Partitioning of the Yeast Cellular Network

    3. No Access

      Chapter

      Pages 351-367

      Systems Biology and Metabolic Engineering in Bacteria

  7. Back Matter

    Pages 369-375