Botulinum Neurotoxins

Editors:

ISBN: 978-3-642-33569-3 (Print) 978-3-642-33570-9 (Online)

Table of contents (14 chapters)

  1. Front Matter

    Pages i-viii

  2. No Access

    Book Chapter

    Pages 1-20

    Genetic Diversity Within Clostridium botulinum Serotypes, Botulinum Neurotoxin Gene Clusters and Toxin Subtypes

  3. No Access

    Book Chapter

    Pages 21-44

    Assembly and Function of the Botulinum Neurotoxin Progenitor Complex

  4. No Access

    Book Chapter

    Pages 45-59

    Uptake of Botulinum Neurotoxin in the Intestine

  5. No Access

    Book Chapter

    Pages 61-90

    Double Receptor Anchorage of Botulinum Neurotoxins Accounts for their Exquisite Neurospecificity

  6. No Access

    Book Chapter

    Pages 91-113

    The Elusive Compass of Clostridial Neurotoxins: Deciding When and Where to Go?

  7. No Access

    Book Chapter

    Pages 115-137

    Synchronized Chaperone Function of Botulinum Neurotoxin Domains Mediates Light Chain Translocation into Neurons

  8. No Access

    Book Chapter

    Pages 139-157

    Clostridial Neurotoxin Light Chains: Devices for SNARE Cleavage Mediated Blockade of Neurotransmission

  9. No Access

    Book Chapter

    Pages 159-177

    Synaptic Vesicle Proteins: Targets and Routes for Botulinum Neurotoxins

  10. No Access

    Book Chapter

    Pages 179-196

    Persistence of Botulinum Neurotoxin Inactivation of Nerve Function

  11. No Access

    Book Chapter

    Pages 197-218

    Structure-Based Drug Discovery for Botulinum Neurotoxins

  12. No Access

    Book Chapter

    Pages 219-255

    Complexity of Botulinum Neurotoxins: Challenges for Detection Technology

  13. No Access

    Book Chapter

    Pages 257-285

    Progress in Cell Based Assays for Botulinum Neurotoxin Detection

  14. No Access

    Book Chapter

    Pages 287-306

    Transforming the Domain Structure of Botulinum Neurotoxins into Novel Therapeutics

  15. No Access

    Book Chapter

    Pages 307-317

    Botulinum Toxin: Application, Safety, and Limitations

  16. Back Matter

    Pages 319-321