2012

Microarrays in Diagnostics and Biomarker Development

Current and Future Applications

Editors:

ISBN: 978-3-642-28202-7 (Print) 978-3-642-28203-4 (Online)

Table of contents (13 chapters)

  1. Front Matter

    Pages i-viii

  2. No Access

    Book Chapter

    Pages 1-8

    The Microarray Paradigm and Its Various Implementations

  3. DNA Arrays

    1. Front Matter

      Pages 9-9

    2. No Access

      Book Chapter

      Pages 11-19

      DNA Arrays in Many Guises

    3. No Access

      Book Chapter

      Pages 21-27

      Expression Profiling for Diagnostics

    4. No Access

      Book Chapter

      Pages 29-38

      Genotype Characterisation for Diagnostics

    5. No Access

      Book Chapter

      Pages 39-52

      Array-CGH and SNP-Arrays, the New Karyotype

  4. Protein (Antigen & Antibody) and Peptide Arrays

    1. Front Matter

      Pages 53-53

    2. No Access

      Book Chapter

      Pages 55-80

      Protein Microarrays and Their Potential Clinical Applications in the Era of Personalized Medicine

    3. No Access

      Book Chapter

      Pages 81-112

      Peptide Arrays

    4. No Access

      Book Chapter

      Pages 113-131

      Slow Off-Rate Modified Aptamer Arrays for Biomarker Discovery and Diagnostic Applications

  5. Other types of arrays

    1. Front Matter

      Pages 133-133

    2. No Access

      Book Chapter

      Pages 135-152

      Tissue Microarrays for Translational Research

    3. No Access

      Book Chapter

      Pages 153-168

      Recent and Future Developments of Microarrays: Miniaturization and Lab-on-Chip Approaches

  6. Data analysis, commercial and regulatory aspects

    1. Front Matter

      Pages 169-169

    2. No Access

      Book Chapter

      Pages 171-210

      Analysis of Array Data and Clinical Validation of Array-Based Assays

    3. No Access

      Book Chapter

      Pages 211-227

      Challenges in the Commercialization of Array-Based Tests

    4. No Access

      Book Chapter

      Pages 229-236

      Genes, Microarrays, and Patents

  7. Back Matter

    Pages 237-240